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CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid...
Phase 1
Durham, North Carolina, United States and 10 other locations
to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic s...
Phase 1, Phase 2
Durham, North Carolina, United States and 33 other locations
allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid...
Phase 3
Chapel Hill, North Carolina, United States and 23 other locations
This Phase 1, multicenter, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (...
Phase 1
Chapel Hill, North Carolina, United States of America and 8 other locations
Ziftomenib is an investigational drug in development for the treatment of patients with acute myeloid leukemia (AML...
Phase 1
Durham, North Carolina, United States and 43 other locations
will be evaluated in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML). The main study has ...
Phase 1, Phase 2
Durham, North Carolina, United States and 55 other locations
This is an open-label, multi-center Phase 1 study of LY3410738, an oral, covalent isocitrate dehydrogenase (IDH) inhibitor, in patients with IDH1 and...
Phase 1
Chapel Hill, North Carolina, United States of America and 36 other locations
with myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML) or acute myeloid leukemia (AML...
Phase 1, Phase 2
Chapel Hill, North Carolina, United States of America and 10 other locations
This is a two Part study in patients with relapsed/refractory acute myeloid leukemia (AML), chronic myelomonocyti...
Phase 1, Phase 2
Durham, North Carolina, United States and 7 other locations
in subjects with relapsed/refractory B cell malignancies or AML after failure of standard therapies or voruciclib in combination with veneto...
Phase 1
Durham, North Carolina, United States and 11 other locations
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