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Find clinical trials for Adenocarcinoma in Boston, MA

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Adenocarcinoma trials near Boston, MA, USA:

Study of Pembrolizumab in Locally Advanced Esophageal Adenocarcinoma

with chemotherapy and chemoradiation in locally advanced esophageal adenocarcinoma to examine the safety and efficacy of the combination of ...

Active, not recruiting
Esophageal Adenocarcinoma
Drug: Carboplatin
Drug: Pembrolizumab

Phase 2

Weill Cornell Medicine (WCM)
Weill Cornell Medicine (WCM)

Providence, Rhode Island, United States and 3 other locations

The purpose of this study is to find out if an experimental drug will prevent metastatic pancreatic adenocarcinoma from becoming resistant t...

Active, not recruiting
Pancreatic Adenocarcinoma Metastatic
Pancreatic Adenocarcinoma
Drug: FOLFIRNINOX
Drug: Losartan

Phase 2

Colin D. Weekes, M.D., PhD

Boston, Massachusetts, United States and 3 other locations

adenocarcinoma. Participants will receive immunotherapy (cemiplimab) which activates the body's immune system to attack cancer cells. Cemip...

Enrolling
Adenocarcinoma of the Pancreas
Adenocarcinoma
Drug: Gemcitabine
Drug: Cemiplimab

Phase 2

Gulam Manji

Providence, Rhode Island, United States and 2 other locations

This study is being done to test the safety and effectiveness of combining ZN-c3 and Gemcitabine in participants with pancreatic cancer.The names of...

Enrolling
Pancreatic Ductal Adenocarcinoma
Advanced Pancreatic Adenocarcinoma
Drug: Gemzar
Drug: Zentalis

Phase 2

Brandon Huffman, MD

Boston, Massachusetts, United States

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Active, not recruiting
PDAC - Pancreatic Ductal Adenocarcinoma
PDAC
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 59 other locations

in individuals with pathologically confirmed pancreatic ductal adenocarcinoma. Following screening, using a standardized administration prot...

Enrolling
Pancreatic Ductal Adenocarcinoma (PDAC)
Drug: [18F]FAPI-74 PET/CT

Phase 3

SOFIE

Boston, Massachusetts, United States and 5 other locations

tislelizumab in patients with advanced/metastatic pancreatic ductal adenocarcinoma (PDAC).The trial will be conducted in two parts (Part 1 a...

Enrolling
Pancreatic Adenocarcinoma Metastatic
Drug: Nab-paclitaxel + Gemcitabine
Drug: Tislelizumab (i.v. 200mg)

Phase 1

Oncomatryx Biopharma

Boston, Massachusetts, United States and 6 other locations

The main goal of this study is to look at the effectiveness and anti-tumor activity (preventing growth of the tumor) of the drugs niraparib and ipili...

Enrolling
Pancreatic Adenocarcinoma Metastatic
Drug: FOLFIRI
Drug: Ipilimumab

Phase 2

Abramson Cancer Center at Penn Medicine
Abramson Cancer Center at Penn Medicine

Boston, Massachusetts, United States and 1 other location

Locations recently updated

first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Active, not recruiting
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Drug: Domvanalimab
Drug: Zimberelimab

Phase 3

Arcus Biosciences
Arcus Biosciences

Boston, Massachusetts, United States and 207 other locations

Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesop...

Enrolling
Metastatic Gastric Adenocarcinoma or Cancer
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
Drug: 5-fluorouracil (5-FU)
Drug: Capecitabine

Phase 3

Astellas
Astellas

Boston, Massachusetts, United States and 169 other locations

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