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(TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The primary hypothesis of this study is sacituzumab tirumote...
Phase 3
Chicago, Illinois, United States and 167 other locations
The objective of this study is to assess safety and efficacy of BA3182 in Advanced Adenocarcinoma...
Phase 1
Chicago, Illinois, United States and 8 other locations
The study population is advanced gastric, gastroesophageal, and esophageal adenocarcinoma participants who have failed upfront standard of c...
Phase 1, Phase 2
Chicago, Illinois, United States and 7 other locations
The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...
Phase 3
Chicago, Illinois, United States and 124 other locations
The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.
Phase 3
Chicago, Illinois, United States and 59 other locations
This study is designed to assess the levels of drug exposure following treatment with tislelizumab administered as a subcutaneous (SC) injection comp...
Phase 3
Hinsdale, Illinois, United States of America and 33 other locations
with chemotherapy in participants with previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma...
Phase 2, Phase 3
Chicago, Illinois, United States and 143 other locations
Claudin 18.2 protein, or CLDN18.2 is a protein found on cells in the digestive system. It is also found on some tumors. Researchers are looking at wa...
Phase 1
Chicago, Illinois, United States and 43 other locations
after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...
Phase 3
Chicago, Illinois, United States and 224 other locations
This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitiza...
Phase 2
Chicago, Illinois, United States and 69 other locations
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