ClinicalTrials.Veeva
Menu

Find clinical trials for Adenocarcinoma in Durham, NC

CTV is a public benefit provided by Veeva Systems to help you find the most relevant clinical trials for you and your loved ones

Related conditions:

Carcinoma
Cancer
Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Esophageal Cancer
Non-Small-Cell Lung Carcinoma

Adenocarcinoma trials near Durham, NC, USA:

Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) (RASolute 302)

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Enrolling
PDAC - Pancreatic Ductal Adenocarcinoma
PDAC
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

Durham, North Carolina, United States and 57 other locations

The purpose of this study is to combine standard radiation therapy with drugs that encourages the body's immune system against cancer cells and simul...

Enrolling
Pancreatic Ductal Adenocarcinoma
Drug: Zimberelimab
Drug: Modified FOLFIRINOX

Phase 2

Gulam Manji

Chapel Hill, North Carolina, United States and 4 other locations

as First-Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma...

Active, not recruiting
Gastric Adenocarcinoma
Gastric Cancer
Drug: Tislelizumab 200mg
Drug: DKN-01 400mg

Phase 2

Leap Therapeutics

Durham, North Carolina, United States and 47 other locations

first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Active, not recruiting
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Drug: Domvanalimab
Drug: Zimberelimab

Phase 3

Arcus Biosciences
Arcus Biosciences

Durham, North Carolina, United States and 210 other locations

This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitiza...

Enrolling
Endometrial Adenocarcinoma
Drug: ACR-368
Drug: Gemcitabine

Phase 2

Acrivon Therapeutics

Chapel Hill, North Carolina, United States and 68 other locations

after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...

Enrolling
Non-small Cell Lung Cancer
Drug: Pemetrexed
Drug: Rilvegostomig

Phase 3

AstraZeneca
AstraZeneca

Durham, North Carolina, United States and 217 other locations

Claudin 18.2 protein, or CLDN18.2 is a protein found on cells in the digestive system. It is also found on some tumors. Researchers are looking at wa...

Enrolling
Gastroesophageal Junction (GEJ) Adenocarcinoma
Pancreatic Adenocarcinoma
Drug: ASP2138
Drug: Irinotecan

Phase 1

Astellas
Astellas

Durham, North Carolina, United States and 41 other locations

Locations recently updated

in participants with untreated metastatic Pancreatic Ductal Adenocarcinoma (PDAC) with homozygous methylthioadenosine phosphorylase (MTAP) d...

Begins enrollment in 3 months
Pancreatic Ductal Adenocarcinoma
Drug: BMS-986504
Drug: Placebo

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Chapel Hill, North Carolina, United States and 258 other locations

efficacy of Spevatamig (PT886). Patients with the following tumor types will be eligible for screening: unresectable or metastatic gastric adenocarcinoma...

Enrolling
Pancreatic Ductal Adenocarcinoma
Gastric or Gastroesophageal Junction Adenocarcinoma
Drug: Gemcitabine
Drug: KEYTRUDA® (pembrolizumab)

Phase 1, Phase 2

Phanes Therapeutics

Durham, North Carolina, United States and 10 other locations

Status recently updated

Some people with pancreatic ductal cancer (PDAC) have a protein called Claudin 18.2 (CLDN18.2) in their tumor. ASP2138 is thought to work by binding...

Not yet enrolling
Enrolling
Pancreatic Ductal Adenocarcinoma
Drug: Irinotecan
Drug: Capecitabine

Phase 1

Astellas
Astellas

Durham, North Carolina, United States

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems