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Find clinical trials for Adenocarcinoma in Indianapolis, IN

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Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Colorectal Cancer
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Esophageal Cancer
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Adenocarcinoma trials near Indianapolis, IN, USA:

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC) (RASolute 304)

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.

Enrolling
Resected Pancreatic Adenocarcinoma
PDAC - Pancreatic Ductal Adenocarcinoma
Drug: daraxonrasib

Phase 3

Revolution Medicines
Revolution Medicines

Indianapolis, Indiana, United States and 6 other locations

resectable or borderline resectable, previously untreated pancreatic adenocarcinoma. The primary objective of this study is to investigate t...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Liposomal Irinotecan
Drug: FOLFOX regimen

Phase 2

University of Florida
University of Florida

Indianapolis, Indiana, United States and 3 other locations

Recently updated

The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Indianapolis, Indiana, United States and 124 other locations

and capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on a first line fluoropy...

Active, not recruiting
Metastatic Pancreatic Adenocarcinoma
Drug: Capecitabine
Drug: Ivaltinostat

Phase 1, Phase 2

CG Pharmaceuticals

Indianapolis, Indiana, United States and 15 other locations

in individuals with pathologically confirmed pancreatic ductal adenocarcinoma. Following screening, using a standardized administration prot...

Enrolling
Pancreatic Ductal Adenocarcinoma (PDAC)
Drug: [18F]FAPI-74 PET/CT

Phase 3

SOFIE

Indianapolis, Indiana, United States and 5 other locations

Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesop...

Enrolling
Metastatic Gastric Adenocarcinoma or Cancer
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
Drug: 5-fluorouracil (5-FU)
Drug: Capecitabine

Phase 3

Astellas
Astellas

Indianapolis, Indiana, United States and 169 other locations

This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitiza...

Enrolling
Endometrial Adenocarcinoma
Drug: ACR-368
Drug: Gemcitabine

Phase 2

Acrivon Therapeutics

Indianapolis, Indiana, United States and 89 other locations

mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior systemic anti-cancer tre...

Enrolling
Adenocarcinoma, Pancreatic Ductal
Drug: mFOLFIRINOX
Drug: Autogene cevumeran

Phase 2

Genentech
Genentech

Indianapolis, Indiana, United States and 89 other locations

This study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery. People ca...

Enrolling
Metastatic Gastric Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Trastuzumab
Drug: Zongertinib

Phase 1, Phase 2

Boehringer Ingelheim
Boehringer Ingelheim

Indianapolis, Indiana, United States and 100 other locations

a dose expansion phase to confirm the dose and combination with bevacizumab. Approximately 500 adult participants with NSCLC, gastroesophageal adenocarcinoma...

Active, not recruiting
Gastroesophageal Adenocarcinoma
Advanced Solid Tumors
Drug: ABBV-400
Drug: Trifluridine/Tipiracil

Phase 1

AbbVie
AbbVie

Indianapolis, Indiana, United States and 86 other locations

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