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resectable or borderline resectable, previously untreated pancreatic adenocarcinoma. The primary objective of this study is to investigate t...
Phase 2
Indianapolis, Indiana, United States and 3 other locations
The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...
Phase 3
Indianapolis, Indiana, United States and 132 other locations
and capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on a first line fluoropy...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 15 other locations
This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitiza...
Phase 2
Indianapolis, Indiana, United States and 68 other locations
mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior systemic anti-cancer tre...
Phase 2
Indianapolis, Indiana, United States and 84 other locations
This study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery. People ca...
Phase 1, Phase 2
Indianapolis, Indiana, United States and 52 other locations
a dose expansion phase to confirm the dose and combination with bevacizumab. Approximately 500 adult participants with NSCLC, gastroesophageal adenocarcinoma...
Phase 1
Indianapolis, Indiana, United States and 84 other locations
This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers.
Phase 1, Phase 2
Indianapolis, Indiana, United States and 12 other locations
A phase 1 imaging study of 68Ga-R10602 in hormone-receptor positive breast cancer.
Phase 1
Indianapolis, Indiana, United States and 4 other locations
The main objective of this study is to compare efficacy of bemarituzumab combined with oxaliplatin, leucovorin, and 5-fluorouracil (5-FU) (mFOLFOX6)...
Phase 3
Indianapolis, Indiana, United States and 300 other locations
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