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Find clinical trials for Adenocarcinoma in St Louis, MO

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Related conditions:

Pancreatic Cancer
Non-Small-Cell Lung Carcinoma
Colorectal Cancer
Stomach Cancer
Carcinoma
Esophageal Cancer
Cancer

Adenocarcinoma trials near St Louis, MO, USA:

Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma

Patients with advanced pancreas adenocarcinoma will be randomized on a 6:1 basis to receive standard of care chemotherapy followed by adapti...

Active, not recruiting
Pancreas Adenocarcinoma
Pancreas Cancer
Drug: Defactinib
Procedure: Research blood draw

Phase 2

The Washington University
The Washington University

St Louis, Missouri, United States

Advanced pancreatic cancer patients receiving treatment of adaptive stereotactic body radiotherapy (SBRT) with concurrent and adjuvant defactinib plu...

Begins enrollment in 2 months
Pancreatic Adenocarcinoma
Pancreas Cancer
Radiation: Stereotactic body radiotherapy
Drug: Avutometinib

Phase 2

The Washington University
The Washington University

Saint Louis, Missouri, United States

The investigators hypothesize that MK2 inhibition may improve efficacy of mFOLFIRINOX chemotherapy for patients with pancreatic ductal adenocarcinoma...

Enrolling
Metastatic Pancreatic Ductal Adenocarcinoma
Cancer of the Pancreas
Drug: mFOLFIRINOX
Drug: Zunsemetinib

Phase 1

The Washington University
The Washington University

Saint Louis, Missouri, United States

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Enrolling
PDAC - Pancreatic Ductal Adenocarcinoma
PDAC
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

St Louis, Missouri, United States and 59 other locations

This study is designed to assess the levels of drug exposure following treatment with tislelizumab administered as a subcutaneous (SC) injection comp...

Enrolling
Metastatic Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Drug: 5-fluorouracil (5-FU)
Drug: Cisplatin

Phase 3

BeiGene
BeiGene

Bridgeton, Missouri, United States and 94 other locations

after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...

Enrolling
Non-small Cell Lung Cancer
Drug: Pemetrexed
Drug: Rilvegostomig

Phase 3

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 221 other locations

and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: Docetaxel
Drug: Irinotecan

Phase 3

AstraZeneca
AstraZeneca

Saint Louis, Missouri, United States and 186 other locations

The purpose of this study is to assess the efficacy and safety of lenvatinib (E7080/MK-7902) plus pembrolizumab (MK-3475) plus chemotherapy compared...

Active, not recruiting
Advanced/Metastatic Gastroesophageal Adenocarcinoma
Drug: 5-FU
Biological: Lenvatinib

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Saint Louis, Missouri, United States and 176 other locations

Barrett's Esophagus (BE), with or without dysplasia, and esophageal adenocarcinoma (EAC) as compared to Esophagogastroduodenoscopy (EGD) plu...

Enrolling
Esophageal Adenocarcinoma
Barretts Esophagus With Dysplasia
Diagnostic Test: Esophagogastroduodenoscopy
Device: EsoGuard (lab assay)
Lucid Diagnostics

Saint Louis, Missouri, United States and 37 other locations

The study will compare the efficacy and safety of pembrolizumab plus trastuzumab in combination with standard of care (SOC) chemotherapy versus trast...

Active, not recruiting
Gastroesophageal Junction Adenocarcinoma
Gastric Neoplasms
Biological: Pembrolizumab
Drug: 5-FU

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

St Louis, Missouri, United States and 191 other locations

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