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Find clinical trials for Alzheimer's Disease in Durham, NC

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Psychotic Disorders
Brain Diseases
Neurodegenerative Diseases

Alzheimer's Disease trials near Durham, NC, USA:

A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease

and efficacy of ONO-2020 in participants with mild to moderate Alzheimer's disease (AD). This study aims to determine whether admin ...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: ONO-2020

Phase 2

Ono Pharmaceuticals
Ono Pharmaceuticals

Raleigh, North Carolina, United States and 23 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Active, not recruiting
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Durham, North Carolina, United States and 109 other locations

This study is a Phase 2b/3 clinical trial of a new candidate drug (T3D-959) to treat patients with mild-to-moderate Alzheimer's. The aims of...

Begins enrollment in a year or more
Alzheimer's Disease
Drug: T3D-959
Other: Placebo Comparator

Phase 2, Phase 3

T3D Therapeutics

Durham, North Carolina, United States

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determin...

Active, not recruiting
Early Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Raleigh, North Carolina, United States and 246 other locations

The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: KarXT

Phase 3

Karuna Therapeutics
Karuna Therapeutics

Greensboro, North Carolina, United States of America and 223 other locations

who were administered gene therapy (LX1001) for the treatment of Alzheimer's disease in Study LX100101. A secondary objective is to...

Invitation-only
Alzheimer Disease
Biological: LX1001

Phase 1

Lexeo Therapeutics

Durham, North Carolina, United States and 1 other location

to alleviate symptoms when given to people with mild to moderate Alzheimer Disease (AD) dementia. This is done by looking at partic...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: Mevidalen

Phase 2

Lilly
Lilly

Raleigh, North Carolina, United States and 63 other locations

The main purpose of this study is to evaluate the safety of LY3954068 in participants with early symptomatic Alzheimer's Disease (A...

Enrolling
Alzheimer Disease
Drug: Flortaucipir F18
Drug: LY3954068

Phase 1

Lilly
Lilly

Durham, North Carolina, United States and 9 other locations

This AR1001-ADP3-US01 protocol is a double-blind, randomized, placebo-controlled, multi- center, parallel-group comparison pivotal Phase 3 study to e...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: AR1001

Phase 3

AriBio

Greensboro, North Carolina, United States of America and 103 other locations

This study is being conducted to evaluate the long-term safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects w...

Active, not recruiting
Early Alzheimer's Disease
Drug: Experimental: ALZ-801

Phase 3

Alzheon

Greensboro, North Carolina, United States of America and 42 other locations

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