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Find clinical trials for Asthma in Philadelphia, PA

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Related conditions:

Allergic Rhinitis
Pulmonary Eosinophilia
Rhinitis
Chronic Obstructive Pulmonary Disease
Dust Mite Allergy
Lung Diseases
Hypersensitivity

Asthma trials near Philadelphia, PA, USA:

REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study

study to evaluate the effect of timely treatment with mepolizumab (NUCALA) to achieve clinical remission in adult participants with severe asthma...

Active, not recruiting
Asthma
Other: Spirometry
Drug: Mepolizumab

Phase 4

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Philadelphia, Pennsylvania, United States and 65 other locations

immunogenicity of APG777 in adult participants with mild-to-moderate asthma.The duration of the study will be approximately 52 weeks (364 da...

Active, not recruiting
Asthma
Drug: Placebo
Drug: APG777

Phase 1

Apogee Therapeutics, Inc.

Philadelphia, Pennsylvania, United States and 12 other locations

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma...

Active, not recruiting
Asthma Attack
Asthma; Eosinophilic
Drug: Dexpramipexole Dihydrochloride
Drug: Placebo

Phase 3

Areteia Therapeutics

Philadelphia, Pennsylvania, United States and 335 other locations

to therapy acting directly on the anti-IL-4R. This will be conducted by examining the effect of a 48 week therapy with dupilumab on the rate of asthma...

Active, not recruiting
Asthma
Other: Placebo
Drug: Dupilumab

Phase 4

Boston Children's Hospital
Boston Children's Hospital

Philadelphia, Pennsylvania, United States and 5 other locations

Asthma is a chronic condition marked by narrowed and swollen airways due to inflammation leading to recurring symptoms that can vary and wor...

Enrolling
Asthma
Biological: Depemokimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Philadelphia, Pennsylvania, United States and 42 other locations

Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solriktug with adult participants with asthma...

Active, not recruiting
Asthma
Biological: NSI-8226
Biological: Placebo

Phase 2

Uniquity One (UNI)

Philadelphia, Pennsylvania, United States and 70 other locations

This study is trying to find the right dose of a long-lasting medicine called GSK5784283 for people with asthma that remains uncontrolled ev...

Active, not recruiting
Asthma
Drug: GSK5784283
Drug: Placebo

Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Philadelphia, Pennsylvania, United States and 138 other locations

trifenatate (FF/UMEC/VI) with inhaled corticosteroids/long-acting beta-2 agonists (ICS/LABA) in adult participants with uncontrolled asthma...

Active, not recruiting
Asthma
Drug: Fluticasone furoate/umeclidinium bromide/vilanterol trifenatate
Drug: Inhaled corticosteroids/long-acting beta-2 agonists

Phase 4

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Philadelphia, Pennsylvania, United States and 116 other locations

The purpose of this study is to assess the PD equivalence of the approved asthma combination therapy, BDA, delivered using the proposed repl....

Active, not recruiting
Asthma
Drug: BDA MDI HFO 160/180 μg
Drug: BDA MDI HFA 160/180 μg

Phase 3

AstraZeneca
AstraZeneca

Pottstown, Pennsylvania, United States and 127 other locations

The study is being conducted to evaluate the effect of 3 dosing regimens of povorcitinib on pulmonary function

Enrolling
Moderate to Severe Asthma
Drug: ICS-LABA
Other: placebo

Phase 2

Incyte
Incyte

Philadelphia, Pennsylvania, United States and 83 other locations

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