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This is a multi-institutional pilot trial for patients with advanced breast cancer. The trial is designed to assess the safety and ...
Phase 1, Phase 2
Salt Lake City, Utah, United States and 1 other location
A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combination in Women with ER Positive, HER2 Negative Advanced Breast Ca...
Phase 1
Salt Lake City, Utah, United States and 16 other locations
to anti-HER2-based therapy plus endocrine therapy alone in improving the outcomes of subjects with hormone receptor-positive, HER2+ metastatic breast...
Phase 3
Salt Lake City, Utah, United States and 106 other locations
postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...
Phase 2
Salt Lake City, Utah, United States and 50 other locations
to see if it can be a possible treatment for advanced metastatic breast cancer. This type of cancer would have spread from...
Phase 1, Phase 2
Salt Lake City, Utah, United States and 53 other locations
This is a first-in-human study of MEN2312, a lysine acetyltransferase 6 (KAT6) inhibitor, in adult participants with advanced breast cancer...
Phase 1
West Valley City, Utah, United States and 19 other locations
The purpose of this study is to test the safety of an investigational drug called CFI-402257 alone in advanced solid tumors and in combinati ...
Phase 1, Phase 2
West Valley City, Utah, United States and 3 other locations
This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...
Phase 3
Ogden, Utah, United States of America and 226 other locations
look at the efficacy and safety of trastuzumab deruxtecan (T-DXd) in a neoadjuvant setting, in high-risk, HER2-positive early non-metastatic breast...
Phase 3
Ogden, Utah, United States and 145 other locations
be open to the enrollment of patients diagnosed with triple-negative breast cancer or ovarian cancer. Dose expansion will ...
Phase 1
Salt Lake City, Utah, United States and 1 other location
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