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Find clinical trials for Breast Cancer in Toronto, ON

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Related conditions:

Triple Negative Breast Cancer
Cancer
Non-Small-Cell Lung Carcinoma
Ovarian Cancer
Neoplasm Metastasis
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer

Breast Cancer trials near Toronto, ON, CAN:

A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer (DB-07)

DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with o ...

Active, not recruiting
Metastatic Breast Cancer
Drug: Tucatinib
Drug: Durvalumab

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Toronto, Canada and 71 other locations

The proposed study will evaluate the safety and efficacy of XRT followed by systemic therapy among patients with HER2+ metastatic breast cancer...

Enrolling
HER2-positive Breast Cancer
LMD
Drug: Capecitabine
Radiation: Brain & Spinal Radiation

Phase 2

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada and 1 other location

to see if it can be a possible treatment for advanced metastatic breast cancer. This type of cancer would have spread from...

Active, not recruiting
Breast Cancer
Drug: vepdegestrant
Drug: PF-07220060

Phase 1, Phase 2

Pfizer
Pfizer

Toronto, Ontario, Canada and 53 other locations

medicines for the potential treatment of advanced or metastatic breast cancer.This study is seeking participants who have breast...

Active, not recruiting
Breast Cancer
Drug: Abemaciclib
Drug: ARV-471

Phase 1, Phase 2

Pfizer
Pfizer

Toronto, Ontario, Canada and 36 other locations

look at the efficacy and safety of trastuzumab deruxtecan (T-DXd) in a neoadjuvant setting, in high-risk, HER2-positive early non-metastatic breast...

Active, not recruiting
HER2-positive Early Breast Cancer
Breast Cancer
Drug: Pertuzumab
Drug: Paclitaxel

Phase 3

AstraZeneca
AstraZeneca

Toronto, Ontario, Canada and 145 other locations

medicines for the potential treatment of advanced or metastatic breast cancer.This study is seeking participants who have breast...

Active, not recruiting
Breast Cancer
Drug: ARV-471
Drug: Ribociclib

Phase 1, Phase 2

Pfizer
Pfizer

Toronto, Ontario, Canada and 28 other locations

A study to learn about a new medicine called ARV-471 (PF-07850327) in people who have advanced metastatic breast cancer....

Active, not recruiting
Advanced Breast Cancer
Drug: ARV-471
Drug: Fulvestrant

Phase 3

Pfizer
Pfizer

Toronto, Ontario, Canada and 316 other locations

The purpose of this study is to find out the effect that CFI-400945 and durvalumab have on breast cancer....

Active, not recruiting
Breast Cancer
Drug: CFI-400945
Drug: Durvalumab

Phase 2

Canadian Cancer Trials Group

Toronto, Ontario, Canada and 4 other locations

+/HER2-) advanced breast cancer....

Enrolling
Advanced HR+/HER2- Breast Cancer
Advanced CCNE1-amplified Solid Tumors
Drug: fulvestrant
Drug: ECI830

Phase 1, Phase 2

Novartis
Novartis

Toronto, Ontario, Canada and 29 other locations

The current study aims to provide validation results of RNA Disruption Assay (RDA) as a tumour response assessment tool that uses tumour core biopsie...

Enrolling
Breast Neoplasm Female
Procedure: Core needle biopsy
Rna Diagnostics Inc.

Toronto, Canada and 6 other locations

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