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Find clinical trials for Chronic Lymphocytic Leukemia in Birmingham, AL

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Non-Hodgkin Lymphoma
Leukemia
Mantle-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
B-Cell Leukemia

Chronic Lymphocytic Leukemia trials near Birmingham, AL, USA:

Addition of Loncastuximab Tesirine to Acalbrutinib , Chronic Lymphocytic Leukemia

Study is a phase I study to determine the maximum tolerated dose of adding Loncastuximab Tesirine to Aclabrutinib in the treatment of chronic...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Loncastuximab Tesirine and Acalabrutinib

Phase 1

The University of Alabama at Birmingham
The University of Alabama at Birmingham

Birmingham, Alabama, United States

Epcoritamab will be tested either inRelapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) as:* Monotherapy, or* Com...

Active, not recruiting
Small Lymphocytic Lymphoma
Treatment-naïve High Risk Chronic Lymphocytic Leukemia
Drug: Lenalidomide
Drug: rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone

Phase 1, Phase 2

Genmab
Genmab

Birmingham, Alabama, United States and 80 other locations

This is a Phase 1/2, open-label, multicenter study to determine the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory CLL...

Active, not recruiting
Lymphoma, Small Lymphocytic
Leukemia, Lymphocytic, Chronic, B-Cell
Biological: JCAR017 (lisocabtagene maraleucel) + venetoclax
Biological: JCAR017 (lisocabtagene maraleucel) + ibrutinib

Phase 1, Phase 2

Juno Therapeutics

Birmingham, Alabama, United States and 83 other locations

with pirtobrutinib in patients with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) or small lymphocytic...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Pirtobrutinib
Drug: Tacabrutideg

Phase 3

BeOne Medicines

Birmingham, Alabama, United States and 217 other locations

This is a Phase I dose-finding study of FT819 as monotherapy and in combination with IL-2 in subjects with relapsed/refractory B-cell Lymphoma, Chronic...

Active, not recruiting
Precursor B-Cell Acute Lymphoblastic Leukemia
Chronic Lymphocytic Leukemia
Drug: Bendamustine
Drug: Fludarabine

Phase 1

Fate Therapeutics
Fate Therapeutics

Birmingham, Alabama, United States and 17 other locations

Study consists of two main parts to explore tacabrutideg recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalat...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Tacabrutideg

Phase 1, Phase 2

BeOne Medicines

Birmingham, Alabama, United States and 117 other locations

The purpose of this clinical trial is to compare drug combinations to learn which drugs work best to prevent graft-versus-host-disease (GVHD) in peop...

Enrolling
Prolymphocyctic Leukemia
Acute Leukemia (Category)
Drug: Post-transplant Abatacept
Drug: Supportive Care: Growth Factors

Phase 2

Center for International Blood and Marrow Transplant Research (CIBMTR)

Birmingham, Alabama, United States and 12 other locations

SLS009 (formerly GFH009) is a potent and highly selective CDK9 inhibitor. In this study the safety, tolerability, and antitumor activity of single ag...

Enrolling
Hematologic Malignancies
Drug: SLS009
Drug: venetoclax

Phase 1, Phase 2

Sellas Life Sciences

Birmingham, Alabama, United States and 31 other locations

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