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Find clinical trials for Chronic Lymphocytic Leukemia in Toronto, ON

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Lymphoma
Lymphoid Leukemia
Mantle-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia trials near Toronto, ON, CAN:

Locations recently updated

A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

This study will evaluate the long-term safety of pirtobrutinib in participants with previously treated chronic lymphocytic leukemia...

Begins enrollment in 2 months
Lymphoma, Small Lymphocytic
Chronic Lymphocytic Leukemia
Drug: Pirtobrutinib
Drug: Idelalisib

Phase 4

Lilly
Lilly

Toronto, Canada and 50 other locations

The purpose of this study is to evaluate the efficacy and safety of ibrutinib + venetoclax (I+V) and ibrutinib monotherapy regimens in which dosing o...

Enrolling
Small Lymphocytic Lymphoma
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: Venetoclax
Drug: Ibrutinib

Phase 2

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

St. Catharines, Ontario, Canada and 74 other locations

objective of this study is to compare the efficacy of sonrotoclax plus zanubrutinib versus venetoclax plus obinutuzumab in participants with chronic...

Active, not recruiting
CLL
Drug: Zanubrutinib
Drug: Sonrotoclax

Phase 3

BeOne Medicines

Toronto, Ontario, Canada and 205 other locations

This is a Phase 1/2, open-label, multicenter study to determine the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory CLL...

Enrolling
Lymphoma, Small Lymphocytic
Leukemia, Lymphocytic, Chronic, B-Cell
Biological: JCAR017 (lisocabtagene maraleucel) + venetoclax
Biological: JCAR017 (lisocabtagene maraleucel) + ibrutinib

Phase 1, Phase 2

Juno Therapeutics

Toronto, Ontario, Canada and 82 other locations

The goal of this study is to evaluate nemtabrutinib compared with investigator's choice of ibrutinib or acalabrutinib in participants with chronic...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Nemtabrutinib
Drug: Acalabrutinib

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Brampton, Ontario, Canada and 190 other locations

The purpose of this study is to assess progression-free survival (PFS) from treatment with ibrutinib plus venetoclax (I+VEN) compared with obinutuzum...

Active, not recruiting
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: Obinutuzumab
Drug: Venetoclax

Phase 3

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Hamilton, Ontario, Canada and 87 other locations

The purpose of this study is to compare the efficacy and safety of fixed duration pirtobruitinib (LOXO-305) with VR (Arm A) compared to VR alone (Arm...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Rituximab

Phase 3

Loxo Oncology
Loxo Oncology

Toronto, Ontario, Canada and 179 other locations

This is a study for patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Pirtobrutinib
Drug: Bendamustine

Phase 3

Loxo Oncology
Loxo Oncology

Toronto, Ontario, Canada and 231 other locations

(CAR) (TBI-2001) for relapsed or refractory CD19+ B-cell lymphoma Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic...

Enrolling
Relapsed or Refractory Small Lymphocytic Lymphoma
Relapsed or Refractory Chronic Lymphocytic Leukemia
Drug: Cyclophosphamide
Drug: Fludarabine

Phase 1

University Health Network, Toronto
University Health Network, Toronto

Toronto, Ontario, Canada

Follicular Lymphoma is a slow-growing type of non-Hodgkin lymphoma. Chronic lymphocytic leukemia (CLL) is the most common ...

Enrolling
Chronic Lymphocytic Leukemia
Follicular Lymphoma
Drug: ABBV-319

Phase 1

AbbVie
AbbVie

Toronto, Ontario, Canada and 19 other locations

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