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Find clinical trials for Colon Cancer in Cleveland, OH

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Related conditions:

Colonic Cancer
Colorectal Cancer
Cancer
Rectal Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer

Colon Cancer trials near Cleveland, OH, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Cleveland, Ohio, United States and 262 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Cleveland, Ohio, United States and 85 other locations

This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced ...

Enrolling
Advanced Solid Cancer
KRAS G12D Mutation
Drug: ARV-806

Phase 1, Phase 2

Arvinas
Arvinas

Cleveland, Ohio, United States and 13 other locations

to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...

Active, not recruiting
Advanced Solid Tumor
Non-small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Cleveland, Ohio, United States and 57 other locations

Locations recently updated

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Cleveland, Ohio, United States and 1055 other locations

in very high numbers).This includes (but limited to) the following cancer types:Non-Small Cell Lung Cancer (NSCLC): It's a type of ...

Enrolling
Colorectal Neoplasms
Carcinoma, Pancreatic Ductal
Combination Product: pemetrexed
Combination Product: Oxaliplatin

Phase 1

Pfizer
Pfizer

Cleveland, Ohio, United States and 27 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Cleveland, Ohio, United States and 231 other locations

in each subject population expansion cohort of advanced solid tumors that harbor a ROS1, NTRK1, NTRK2, or NTRK3 gene rearrangement. The seco...

Enrolling
Locally Advanced Solid Tumors
Metastatic Solid Tumors
Drug: Oral repotrectinib (TPX-0005)

Phase 1, Phase 2

Turning Point Therapeutics
Turning Point Therapeutics

Cleveland, Ohio, United States and 163 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Cleveland, Ohio, United States and 269 other locations

This multi-site, Phase 1/2a clinical trial is an open-label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen o...

Enrolling
Glioblastoma Multiforme
Drug: Perillyl alcohol

Phase 1, Phase 2

NeOnc Technologies

Cleveland, Ohio, United States and 11 other locations

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