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Find clinical trials for Colon Cancer in London, England

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Related conditions:

Colonic Cancer
Colorectal Cancer
Cancer
Rectal Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer

Colon Cancer trials near London, England, GBR:

A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer (AZUR-4)

." . The aim is to see if this new approach can show early signs of effectiveness in treating participants with a specific type of colon cancer...

Enrolling
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

London, United Kingdom and 31 other locations

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

London, United Kingdom and 262 other locations

A significant proportion of patients who undergo liver surgery to remove bowel cancer that has spread to the liver (metastases) develop dise...

Active, not recruiting
Colon Cancer
Liver Metastasis
Drug: Icosapent Ethyl
Other: Placebo

Phase 3

Mark A Hull, PhD FRCP

London, United Kingdom and 12 other locations

The purpose of this study is to assess the safety and tolerability of XmAb®819 administered intravenous (IV) or subcutaneous (SC) in subjects with re...

Enrolling
Clear Cell Renal Cell Carcinoma
Biological: XmAb819

Phase 1

Xencor
Xencor

Cambridge, Cambridgeshire, United Kingdom and 23 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

London, United Kingdom and 85 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: Selpercatinib

Phase 1, Phase 2

Lilly
Lilly

London, Greater London, United Kingdom and 25 other locations

trial is to determine the safety and efficacy of IP-001 for intratumoral injection administration following thermal ablation of a solid tumor...

Active, not recruiting
Nonsmall Cell Lung Cancer
Colon Cancer
Drug: 1.0% IP-001 for Injection

Phase 1, Phase 2

Immunophotonics

London, United Kingdom and 15 other locations

Recently updated

chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer....

Enrolling
CRC (Colorectal Cancer)
Drug: INCA33890
Drug: Placebo

Phase 3

Incyte
Incyte

London, United Kingdom and 273 other locations

pembrolizumab or irinotecan that can be given to patients who have cancers with specific molecular alterations called MSIhi (Microsatellite ...

Active, not recruiting
MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Biological: pembrolizumab
Drug: HRO761

Phase 1

Novartis
Novartis

London, United Kingdom and 27 other locations

in each subject population expansion cohort of advanced solid tumors that harbor a ROS1, NTRK1, NTRK2, or NTRK3 gene rearrangement. The seco...

Enrolling
Locally Advanced Solid Tumors
Metastatic Solid Tumors
Drug: Oral repotrectinib (TPX-0005)

Phase 1, Phase 2

Turning Point Therapeutics
Turning Point Therapeutics

London, United Kingdom and 163 other locations

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