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of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/β-catenin signaling pathw...
Phase 1
Seattle, Washington, United States and 10 other locations
To confirm the safety and performance of the da Vinci SP Surgical System, Instruments and Accessories in a complex colorectal procedure such as low a...
Tacoma, Washington, United States and 8 other locations
This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of ....
Phase 1
Seattle, Washington, United States and 7 other locations
oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...
Phase 1, Phase 2
Seattle, Washington, United States and 25 other locations
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...
Phase 2, Phase 3
Seattle, Washington, United States and 944 other locations
known as MVC-101) in adults with unremovable advanced or metastatic cancer. Another aim is to characterize and evaluate the activity of TAK-...
Phase 1, Phase 2
Seattle, Washington, United States and 27 other locations
to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...
Phase 1
Seattle, Washington, United States and 54 other locations
The goal of this study is to test A2B694, an autologous logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorec...
Phase 1, Phase 2
Seattle, Washington, United States and 10 other locations
with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...
Phase 3
Seattle, Washington, United States and 274 other locations
evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...
Phase 1, Phase 2
Seattle, Washington, United States of America and 233 other locations
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