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The study is a prospective, randomized, 52-week double-blind, placebo-controlled, multicenter trial in subjects with T1D followed by a 2-year safety...
Phase 2
Chapel Hill, North Carolina, United States and 22 other locations
blood sugar that sometimes happens when injecting insulin in Type 1 diabetes patients. Participants will use continuous glucose monitoring t...
Phase 2
Chapel Hill, North Carolina, United States and 26 other locations
Objectives The objective of this clinical trial is to assess whether ladarixin treatment has an effect to preserve β-cell function and delay the prog...
Phase 2
Raleigh, North Carolina, United States and 56 other locations
OPL-0401-201 is a multicenter study to investigate the safety and efficacy of OPL-0401 in patients with diabetes mellitus (DM) with diabetic...
Phase 2
Wake Forest, North Carolina, United States of America and 24 other locations
The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and...
Phase 3
Chapel Hill, North Carolina, United States and 78 other locations
IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes...
Durham, North Carolina, United States and 5 other locations
implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes...
Durham, North Carolina, United States
This is a Phase 3 trial of cadisegliatin as adjunctive therapy to insulin in participants with Type 1 Diabetes Mellitus....
Phase 3
Chapel Hill, North Carolina, United States of America and 22 other locations
This study is a Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple a...
Phase 1, Phase 2
Raleigh, North Carolina, United States and 13 other locations
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes...
Phase 3
Chapel Hill, North Carolina, United States and 80 other locations
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