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The purpose of this study is to assess the safety and pharmacokinetics (PK) of teplizumab in participants with Stage 2 type 1 diabetes who a...
Phase 4
Indianapolis, Indiana, United States and 9 other locations
Objectives The objective of this clinical trial is to assess whether ladarixin treatment has an effect to preserve β-cell function and delay the prog...
Phase 2
Indianapolis, Indiana, United States and 56 other locations
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question\[s\] it aims to answ...
Phase 2
Indianapolis, Indiana, United States and 5 other locations
The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and...
Phase 3
Fishers, Indiana, United States and 78 other locations
Closed Loop system (HCL) in adult and pediatric patients with type 1 diabetes in the home setting. A diverse population of patients with typ...
Indianapolis, Indiana, United States and 35 other locations
The goal of this clinical trial is to learn if the twiist insulin delivery system works to treat adults with insulin-treated type 2 diabetes....
Indianapolis, Indiana, United States and 23 other locations
control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes...
Phase 2
Indianapolis, Indiana, United States and 26 other locations
This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medic...
Phase 3
Avon, Indiana, United States and 180 other locations
This study compares 2 medicines for type 2 diabetes: semaglutide (new medicine) and a dummy medicine (placebo). Semaglutide will be tested t...
Phase 3
Indianapolis, Indiana, United States and 65 other locations
The goal of this clinical trial is to learn about the effect of the study drug (ZT-01) on low blood sugar (hypoglycemia) in adults with type 1 diabetes...
Phase 2
Indianapolis, Indiana, United States and 25 other locations
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