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The purpose of this study is to investigate the efficacy and safety of the lifileucel regimen in participants with previously treated endometrial...
Phase 2
Detroit, Michigan, United States and 6 other locations
letrozole in advanced stage, persistent or recurrent endometrioid endometrial cancer at 6 months. Treatment will continue until eit...
Phase 2
Ann Arbor, Michigan, United States and 28 other locations
This is a multicenter, open-label, nonrandomized, Phase 2 umbrella study of retifanlimab in participants who have advanced or metastatic endometrial...
Phase 2
Detroit, Michigan, United States and 65 other locations
DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + rilvegostomig (Arm A) and/or T-DXd+ pembrolizumab (Arm B) when com...
Phase 3
Ann Arbor, Michigan, United States and 210 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Detroit, Michigan, United States and 168 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
Detroit, Michigan, United States and 16 other locations
in patients with ROR1+ relapsed or refractory triple negative breast cancer (TNBC), non-small cell lung cancer (NSCLC), platinum-re ...
Phase 1
Detroit, Michigan, United States and 17 other locations
safe and well tolerated, and to determine an optimal and safe dose(s) for further study. The study will also evaluate the effect of XmAb541 on tumor...
Phase 1
Detroit, Michigan, United States and 8 other locations
The purpose of this study is to characterize the safety and tolerability of ALTA2618 in adults with AKT1 E17K-mutant advanced solid tumors....
Phase 1
Maumee, Ohio, United States and 39 other locations
This study will test the safety, including side effects, and determine the characteristics of a drug called Rina-S in participants with solid tumors...
Phase 1, Phase 2
Detroit, Michigan, United States and 36 other locations
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