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(MMR) system, that fixes genetic mistakes. In most endometrial cancers, this system works normally, and these cancers are ...
Phase 3
Austin, Texas, United States and 42 other locations
This is a Phase III, 2-arm, randomized, open label, multicenter, global study assessing the efficacy and safety of puxitatug samrotecan compared to p...
Phase 3
Austin, Texas, United States and 318 other locations
DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + rilvegostomig (Arm A) and/or T-DXd+ pembrolizumab (Arm B) when com...
Phase 3
Austin, Texas, United States and 253 other locations
This study evaluates navtemadlin as maintenance treatment for patients with advanced or recurrent endometrial cancer (EC) who have ...
Phase 2, Phase 3
Austin, Texas, United States and 83 other locations
standard medical care for the treatment of recurrent or progressive endometrial cancer (EC) following prior therapy. There is an eq...
Phase 3
Austin, Texas, United States and 178 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Austin, Texas, United States and 168 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
Austin, Texas, United States and 16 other locations
HWK-007-101 is a multicenter, open-label, first-in-human (FIH) Phase 1 study evaluating HWK-007, a protein tyrosine kinase 7 (PTK7)-targeted antibody...
Phase 1
Austin, Texas, United States and 11 other locations
in participants with solid tumors.Participants will have solid tumor cancer that has spread through the body (metastatic) or cannot be remov...
Phase 1, Phase 2
Austin, Texas, United States and 65 other locations
This is a Phase 1, two-part, open-label, nonrandomized, dose-escalation and signal-seeking study of CGT6297, evaluating the safety, tolerability, PK,...
Phase 1
Austin, Texas, United States and 10 other locations
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