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This is a Phase III, 2-arm, randomized, open label, multicenter, global study assessing the efficacy and safety of puxitatug samrotecan compared to p...
Phase 3
Cleveland, Ohio, United States and 181 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Cleveland, Ohio, United States and 202 other locations
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer...
Phase 3
Cleveland, Ohio, United States and 190 other locations
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Cleveland, Ohio, United States and 168 other locations
to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial...
Phase 2
Cleveland, Ohio, United States and 69 other locations
pharmacokinetics, pharmacodynamics, maximum tolerated dose, and anti-tumor effects of AVZO-021 in patients with advanced solid tumors...
Phase 1, Phase 2
Cleveland, Ohio, United States and 12 other locations
first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer...
Phase 1
Cleveland, Ohio, United States and 13 other locations
The purpose of this trial is to measure the following in participants with solid tumors who receive GEN1047:* The side effects seen with GEN...
Phase 1, Phase 2
Cleveland, Ohio, United States and 35 other locations
administered orally in adults with AKT1 E17K-mutant, advanced solid tumors and also in HR+/HER2- advanced and metastatic breast cancer...
Phase 1
Cleveland, Ohio, United States and 9 other locations
dose (RP2D) of E7386 in combination with other anticancer drug(s), and to determine the optimal dose of E7386 in combination with lenvatinib in endometrial...
Phase 1, Phase 2
Cleveland, Ohio, United States and 106 other locations
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