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study to evaluate the efficacy and safety of sapanisertib and serabelisib (PIKTOR) with paclitaxel in participants with advanced or recurrent endometrial...
Phase 2
Doylestown, Pennsylvania, United States and 13 other locations
letrozole in advanced stage, persistent or recurrent endometrioid endometrial cancer at 6 months. Treatment will continue until eit...
Phase 2
Willow Grove, Pennsylvania, United States and 28 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
Camden, New Jersey, United States and 202 other locations
DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + rilvegostomig (Arm A) and/or T-DXd+ pembrolizumab (Arm B) when com...
Phase 3
Abington, Pennsylvania, United States and 210 other locations
Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with plati...
Phase 3
Philadelphia, Pennsylvania, United States and 241 other locations
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer...
Phase 3
Philadelphia, Pennsylvania, United States and 161 other locations
This phase II trial studies the effect of onapristone and anastrozole in treating patients with hormone receptor positive endometrial cancer...
Phase 2
Philadelphia, Pennsylvania, United States and 1 other location
participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....
Phase 3
Philadelphia, Pennsylvania, United States and 168 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
Philadelphia, Pennsylvania, United States and 16 other locations
To demonstrate the efficacy and safety of the combination of rucaparib, bevacizumab and atezolizumab in recurrent, progressive endometrial c...
Phase 2
Bethlehem, Pennsylvania, United States and 2 other locations
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