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Find clinical trials for Endometrial Cancer in Pittsburgh, PA

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Cancer
Carcinoma
Ovarian Cancer
Breast Cancer
Triple Negative Breast Cancer
Ovarian Epithelial Carcinoma
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Endometrial Cancer trials near Pittsburgh, PA, USA:

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

The purpose of this study is to investigate the efficacy and safety of the lifileucel regimen in participants with previously treated endometrial...

Enrolling
Endometrial Cancer
Biological: Lifileucel

Phase 2

Iovance Biotherapeutics

Pittsburgh, Pennsylvania, United States and 8 other locations

Locations recently updated

study to evaluate the efficacy and safety of sapanisertib and serabelisib (PIKTOR) with paclitaxel in participants with advanced or recurrent endometrial...

Enrolling
Endometrial Cancer
Drug: Serabelisib
Drug: Paclitaxel

Phase 2

Faeth Therapeutics

Pittsburgh, Pennsylvania, United States and 15 other locations

This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune check ...

Enrolling
Endometrial Cancer
Drug: Talazoparib
Drug: Bevacizumab

Phase 1, Phase 2

Alliance Foundation Trials

Pittsburgh, Pennsylvania, United States and 20 other locations

study is designed to evaluate the efficacy, safety, and pharmacokinetics of giredestrant monotherapy in participants with Grade 1 endometrioid endometrial...

Active, not recruiting
Endometrial Cancer
Drug: Giredestrant

Phase 2

Roche
Roche

Pittsburgh, Pennsylvania, United States and 12 other locations

Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with plati...

Enrolling
Endometrial Cancer
Drug: Paclitaxel
Drug: Nab-paclitaxel

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Pittsburgh, Pennsylvania, United States and 242 other locations

DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + rilvegostomig (Arm A) and/or T-DXd+ pembrolizumab (Arm B) when com...

Enrolling
Endometrial Cancer
Drug: Carboplatin
Drug: Paclitaxel

Phase 3

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 232 other locations

(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...

Active, not recruiting
Endometrial Neoplasms
Drug: Carboplatin
Biological: durvalumab

Phase 3

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 202 other locations

participants with recurrent or primary advanced (Stage III or IV) endometrial cancer....

Active, not recruiting
Neoplasms
Drug: Paclitaxel
Drug: Carboplatin

Phase 3

Tesaro
Tesaro

Pittsburgh, Pennsylvania, United States and 168 other locations

to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial...

Enrolling
Endometrial Adenocarcinoma
Drug: ACR-368
Drug: Gemcitabine

Phase 2

Acrivon Therapeutics

Pittsburgh, Pennsylvania, United States and 68 other locations

T-cell therapy product genetically engineered to express an HLA-C\*08:02-restricted T cell receptor (TCR), targeting KRAS G12D mutant solid tumors...

Active, not recruiting
Endometrial Cancer
Solid Tumor, Adult
Biological: NT-112: Autologous, engineered T Cells targeting KRAS G12D

Phase 1

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 12 other locations

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