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study to evaluate the efficacy and safety of sapanisertib and serabelisib (PIKTOR) with paclitaxel in participants with advanced or recurrent endometrial...
Phase 2
La Jolla, California, United States and 15 other locations
(paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial...
Phase 3
La Jolla, California, United States and 202 other locations
DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd + rilvegostomig (Arm A) and/or T-DXd+ pembrolizumab (Arm B) when com...
Phase 3
La Jolla, California, United States and 232 other locations
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer...
Phase 3
La Jolla, California, United States and 170 other locations
to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial...
Phase 2
La Jolla, California, United States and 68 other locations
This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in...
Phase 2
La Jolla, California, United States of America and 16 other locations
The purpose of this study is to characterize the safety and tolerability of ALTA2618 in adults with AKT1 E17K-mutant advanced solid tumors....
Phase 1
La Jolla, California, United States and 41 other locations
This study will test the safety, including side effects, and determine the characteristics of a drug called Rina-S in participants with solid tumors...
Phase 1, Phase 2
San Diego, California, United States and 36 other locations
This research is designed to determine if experimental treatment with Antibody-drug conjugate, AZD5335, alone, or in combination with anti-cancer...
Phase 1, Phase 2
La Jolla, California, United States and 58 other locations
antitumor activity of IMGN151 in adult participants with recurrent endometrial cancer; recurrent, high-grade serous epithelial ovar...
Phase 1
La Jolla, California, United States and 28 other locations
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