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efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...
Phase 1, Phase 2
Houston, Texas, United States and 20 other locations
(SOC) will improve survival in adult patients newly diagnosed with glioblastoma (IDH-wt). It will also evaluate the safety of DOC1021 + pIFN...
Phase 2
Houston, Texas, United States and 2 other locations
In summary, standard of care postoperative chemoradiation for patients with newly diagnosed GBM does not routinely provide durable local con...
Phase 4
Houston, Texas, United States and 15 other locations
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
Houston, Texas, United States and 61 other locations
Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...
Phase 3
Houston, Texas, United States and 35 other locations
of O-6-methylguanine-DNA methyltransferase (MGMT) unmethylated glioblastoma with VAL-083 improves overall survival (OS), compared to histori...
Phase 2
Houston, Texas, United States
This phase I trial studies best dose and side effects of oncolytic adenovirus DNX-2401 in treating patients with high-grade glioma that has come back...
Phase 1
Houston, Texas, United States
and tolerability of these combinations in adult participants with glioblastoma (GBM). Arm B which was previously added to the proto...
Phase 1, Phase 2
Houston, Texas, United States and 16 other locations
This research study is studying a targeted therapy as a possible treatment for recurrent glioblastoma (GBM).The following intervent...
Phase 2
Houston, Texas, United States and 6 other locations
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...
Phase 2
Houston, Texas, United States and 11 other locations
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