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Find clinical trials for Glioblastoma (GBM) in Houston, TX

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Related conditions:

Glioblastoma
Recurrence
Glioma
Brain Cancer
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near Houston, TX, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting
Glioblastoma
Drug: Temozolomide
Biological: INO-9012

Phase 1, Phase 2

Inovio Pharmaceuticals
Inovio Pharmaceuticals

Houston, Texas, United States and 20 other locations

Locations recently updated

(SOC) will improve survival in adult patients newly diagnosed with glioblastoma (IDH-wt). It will also evaluate the safety of DOC1021 + pIFN...

Enrolling
Glioblastoma (GBM)
Drug: Temodar (Temozolomide)
Biological: DOC1021

Phase 2

Diakonos Oncology Corporation

Houston, Texas, United States and 2 other locations

In summary, standard of care postoperative chemoradiation for patients with newly diagnosed GBM does not routinely provide durable local con...

Enrolling
Glioblastoma
Device: Surgical tumor resection, GammaTile radiation therapy implantation, Stupp protocol (EBRT and Temozolamide)

Phase 4

GT Medical Technologies

Houston, Texas, United States and 15 other locations

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Drug: Temozolomide
Radiation: Radiation

Phase 2, Phase 3

Global Coalition for Adaptive Research

Houston, Texas, United States and 61 other locations

Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...

Enrolling
Glioblastoma
Drug: Temozolomide
Drug: Placebo

Phase 3

NovoCure
NovoCure

Houston, Texas, United States and 35 other locations

of O-6-methylguanine-DNA methyltransferase (MGMT) unmethylated glioblastoma with VAL-083 improves overall survival (OS), compared to histori...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: VAL-083, Dianhydrogalactitol

Phase 2

Kintara Therapeutics

Houston, Texas, United States

This phase I trial studies best dose and side effects of oncolytic adenovirus DNX-2401 in treating patients with high-grade glioma that has come back...

Enrolling
Recurrent Glioblastoma
IDH1 wt Allele
Biological: Oncolytic Adenovirus Ad5-DNX-2401
Procedure: Therapeutic Conventional Surgery

Phase 1

M.D. Anderson Cancer Center
M.D. Anderson Cancer Center

Houston, Texas, United States

and tolerability of these combinations in adult participants with glioblastoma (GBM). Arm B which was previously added to the proto...

Enrolling
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Astrocytoma, Grade III
Drug: Debio 0123
Drug: Temozolomide

Phase 1, Phase 2

Debiopharm
Debiopharm

Houston, Texas, United States and 16 other locations

This research study is studying a targeted therapy as a possible treatment for recurrent glioblastoma (GBM).The following intervent...

Active, not recruiting
Glioblastoma
Procedure: Surgery
Drug: Abemaciclib

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Houston, Texas, United States and 6 other locations

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...

Enrolling
Glioblastoma
Drug: Neratinib
Drug: Temozolomide

Phase 2

Patrick Wen, MD

Houston, Texas, United States and 11 other locations

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