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the safety of MT-125 in participants who have been diagnosed with glioblastoma, a primary brain tumor, when administered in combination with...
Phase 1
Rochester, Minnesota, United States and 2 other locations
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
Rochester, Minnesota, United States and 61 other locations
Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...
Phase 3
Rochester, Minnesota, United States and 55 other locations
with or without epacadostat in the treatment of recurrent glioblastoma (GBM). The investigators hypothesize that this combination p...
Phase 2
Rochester, Minnesota, United States and 3 other locations
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...
Phase 2
Rochester, Minnesota, United States and 11 other locations
are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...
Phase 3
Rochester, Minnesota, United States and 47 other locations
growth factor receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM...
Phase 1, Phase 2
Rochester, Minnesota, United States and 43 other locations
This phase II trial tests the safety and side effects of efineptakin alfa and pembrolizumab in treating patients with glioblastoma that has ...
Phase 2
Rochester, Minnesota, United States
This is an open-label, multicenter, randomized, parallel, 2-arm, efficacy and safety study. Patients with GBM after failure of standard firs...
Phase 2
Rochester, Minnesota, United States and 47 other locations
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