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FRONTIER Study is a prospective, interventional, single-arm, multi-center, study to assess the safety and technical feasibility of TheraSphere GBM...
Phase 1
Baltimore, Maryland, United States and 8 other locations
This is a Phase 3 prospective, randomized, superiority, open-label, multi-site study. The overview of this study is as follows:* A Screening/Baseline...
Phase 3
Fairfax, Virginia, United States and 12 other locations
The purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma...
Phase 2
Washington D.C., District of Columbia, United States and 31 other locations
the feasibility of adding MRSI to the evaluation of newly-diagnosed GBM patients treated with standard RT/TMZ and determine whether magnetic...
Phase 2
Baltimore, Maryland, United States and 1 other location
Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...
Phase 3
Washington D.C., District of Columbia, United States and 101 other locations
are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...
Phase 3
Baltimore, Maryland, United States and 55 other locations
growth factor receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM...
Phase 1, Phase 2
Washington D.C., District of Columbia, United States and 28 other locations
This clinical trial is testing the safety and efficacy of NanO2TM administered via intravenous infusion in combination with standard radiation and ch...
Phase 2
Fairfax, Virginia, United States and 11 other locations
via ICV in participants with recurrent or progressive IDH-wildtype glioblastoma (WHO 2021 CNS Grade 4), who have previously received standar...
Phase 2
Baltimore, Maryland, United States and 3 other locations
A), advanced solid tumors (Cohort B), or recurrent or progressive GBM (Cohort C) (collectively called 'indication cohorts'). Participants ag...
Phase 1
Fairfax, Virginia, United States
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