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Find clinical trials for Heart Disease in London, England

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Related conditions:

Heart Diseases
Cardiovascular Diseases
Coronary Artery Disease
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Mitral Valve Insufficiency

Heart Disease trials near London, England, GBR:

PROTEUS: Evaluating the Use of Artificial Intelligence to Support Stress Echocardiography Testing for Heart Disease

PROTEUS is a multicentre, two arm, randomised controlled trial of a medical device to assess the impact of the introduction of EchoGo into the standa...

Active, not recruiting
Coronary Heart Disease
Diagnostic Test: EchoGo
Ultromics

London, United Kingdom and 19 other locations

The purpose is to compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifur...

Active, not recruiting
Ischemic Heart Disease
Ischaemic Heart Disease
Procedure: Angiographic guided PCI
Procedure: OCT guided PCI
Aarhus University Hospital Skejby

London, United Kingdom and 37 other locations

Familial Hypercholesterolemia (HeFH) or Premature Coronary Artery Disease (CAD) Who Require Additional Lowering of LDL-C. VERVE-102 Uses Bas...

Enrolling
Premature Coronary Heart Disease
Heterozygous Familial Hypercholesterolemia
Drug: VERVE-102

Phase 1

Verve Therapeutics

London, United Kingdom and 21 other locations

diagnostic procedure (IDP) during the invasive management of patients with known or suspected angina but no obstructive coronary artery disease...

Enrolling
Coronary Artery Disease
Ischaemic Heart Disease
Other: IDP performed but results not disclosed
Diagnostic Test: Disclosure of IDP results
NHS Trust
NHS Trust

London, United Kingdom and 38 other locations

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic h...

Active, not recruiting
Heart Transplantation
Device: XVIVO heart preservation devices
Device: Standard ICSS
XVIVO
XVIVO

Cambridge, United Kingdom and 14 other locations

Evaluation of TAVR using the NAVITOR valve in a Global Investigation.

Active, not recruiting
Symptomatic Severe Aortic Stenosis
Device: Navitor Transcatheter Aortic valve and FlexNav Delivery system
Abbott
Abbott

London, United Kingdom and 36 other locations

The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardia...

Enrolling
Atherosclerotic Coronary Vascular Disease
Coronary Arterial Disease (CAD)
Drug: Placebo
Drug: Orticumab

Phase 2

Abcentra

London, Greater London, United Kingdom and 40 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

London, United Kingdom and 83 other locations

with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac...

Active, not recruiting
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

London, United Kingdom and 161 other locations

The primary objective of this study is to characterize the efficacy and safety of dosing regimens used to transition from prior pericarditis therapie...

Enrolling
Heart Diseases
Pericarditis
Drug: KPL-387

Phase 2

Kiniksa Pharmaceuticals International, plc

London, United Kingdom and 11 other locations

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