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Find clinical trials for Heart Disease in Louisville, KY

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Related conditions:

Heart Diseases
Coronary Artery Disease
Cardiovascular Diseases
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Coronary Disease

Heart Disease trials near Louisville, KY, USA:

PROACTIVE-HF IDE Trial Heart Failure NYHA Class III

open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System in NYHA Class III Heart...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System
Endotronix

Louisville, Kentucky, United States and 73 other locations

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon
Abbott
Abbott

Louisville, Kentucky, United States and 103 other locations

The goal of this clinical trial is to is to test the safety of a new way to deliver a commonly used drug (amiodarone) used in heart surgery ...

Enrolling
Atrial Fibrillation, Postoperative
Combination Product: The intervention includes Amiodarone-Infused CardiaMend patches (70mg, 150mg and 300mg)

Phase 1, Phase 2

Helios Cardio Inc.

Louisville, Kentucky, United States

who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease. The trial tests...

Enrolling
Diabetes Mellitus, Type 2
Metabolic Syndrome
Device: The Cleerly CAD Staging System
Cleerly

Louisville, Kentucky, United States and 96 other locations

Locations recently updated

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications o...

Enrolling
Atherosclerotic Cardiovascular Disease (ASCVD)
Chronic Kidney Disease (CKD)
Drug: Retatrutide
Drug: Placebo

Phase 3

Lilly
Lilly

Louisville, Kentucky, United States and 833 other locations

This study will look at the effects of CagriSema on cardiovascular events (for example heart attack and stroke) in people living with cardio...

Active, not recruiting
Cardiovascular Disease
Drug: Cagrilintide
Drug: Semaglutide

Phase 3

Novo Nordisk
Novo Nordisk

Louisville, Kentucky, United States and 569 other locations

The primary objective of this study is to compare the effect of treatment with olpasiran, to placebo, on the risk for coronary heart disease...

Active, not recruiting
Atherosclerotic Cardiovascular Disease
Drug: Olpasiran
Drug: Placebo

Phase 3

Amgen
Amgen

Louisville, Kentucky, United States and 737 other locations

cardiovascular events (MACE) including coronary heart disease (CHD) death, ischemic stroke, myocardial infarction (MI), acute limb...

Active, not recruiting
Arteriosclerosis
Hypercholesterolaemia
Drug: Placebo
Drug: Enlicitide Decanoate

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Louisville, Kentucky, United States and 672 other locations

Locations recently updated

The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. ...

Enrolling
Acute Myocardial Infarction (AMI)
Cardiovascular Risk
Drug: Ziltivekimab
Drug: Placebo

Phase 3

Novo Nordisk
Novo Nordisk

Louisville, Kentucky, United States and 805 other locations

The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipi...

Active, not recruiting
Cardiovascular Disease
Stroke
Drug: Evolocumab
Drug: Routine Lipid Management

Phase 4

Amgen
Amgen

Louisville, Kentucky, United States and 119 other locations

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