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Find clinical trials for Heart Disease in Philadelphia, PA

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Related conditions:

Heart Diseases
Cardiovascular Diseases
Coronary Artery Disease
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Mitral Valve Insufficiency

Heart Disease trials near Philadelphia, PA, USA:

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Sphere-9 VT EFS is a prospective, multi-center, non-randomized, unblinded feasibility study. Adult subjects with recurrent, sustained, scar-related m...

Enrolling
Ventricular Tachycardia (VT)
Device: Sphere-9 Catheter with the Affera Mapping and Ablation System
Medtronic Cardiac Ablation Solutions

Philadelphia, Pennsylvania, United States and 5 other locations

evaluate the safety and efficacy of Synchronized Diaphragmatic Stimulation delivered using the VisONE System in the treatment of patients with heart...

Enrolling
Heart Failure With Reduced Ejection Fraction
Device: Synchronized Diaphragmatic Stimulation
VisCardia

Philadelphia, Pennsylvania, United States

The study will evaluate the impact of a combined device-drug strategy with Impella 5.5 with best practices and optimized GDMT on heart recov...

Not yet enrolling
Heart Failure
Reduced Ejection Fraction Heart Failure
Device: Impella 5.5 SmartAssist
Abiomed
Abiomed

Philadelphia, Pennsylvania, United States and 6 other locations

evaluating the safety and efficacy of dual chamber personalized pacing compared to minimal or no pacing for the treatment of patients with heart...

Enrolling
Heart Failure With Preserved Ejection Fraction (HFpEF)
Device: Personalized cardiac pacing
Medtronic
Medtronic

Wynnewood, Pennsylvania, United States and 41 other locations

Locations recently updated

) application in patients with symptomatic heart disease due to failure of a surgical or transcatheter bioprosthetic aortic valve w...

Invitation-only
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

Wynnewood, Pennsylvania, United States and 84 other locations

knowledge impacts physician/provider behavior as well as clinical outcomes including cholesterol levels and incident heart disease....

Invitation-only
Coronary Artery Disease
Cardiovascular Diseases
Genetic: Disclosure of integrate risk score for coronary artery disease
MyOme

Philadelphia, Pennsylvania, United States and 1 other location

The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Dr...

Invitation-only
Transplant; Failure, Heart
Congenital Heart Disease
Device: EXCOR Active Driving System for Pediatric VAD
Berlin Heart

Philadelphia, Pennsylvania, United States and 14 other locations

Prospective, single-arm, multi-center study to evaluate safety and effectiveness of the Autus Size-Adjustable Valve in pediatric patients aged 18 mon...

Active, not recruiting
Congenital Heart Disease
Device: Pulmonary Valve Replacement Surgery
Autus Valve Technologies

Philadelphia, Pennsylvania, United States and 11 other locations

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo...

Enrolling
Single Ventricle Heart Disease
Drug: Placebo
Drug: Udenafil

Phase 3

Mezzion Pharmaceuticals

Philadelphia, Pennsylvania, United States and 39 other locations

To demonstrate the safety and effectiveness of the Edwards Alterra Adaptive Prestent in conjunction with the Edwards SAPIEN 3 Transcatheter Heart...

Active, not recruiting
Pulmonary Disease
Congenital Heart Disease
Device: Edwards Alterra Adaptive Prestent with SAPIEN 3 THV
Edwards Lifesciences
Edwards Lifesciences

Philadelphia, Pennsylvania, United States and 13 other locations

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