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Find clinical trials for Heart Disease in Toronto, ON

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Related conditions:

Heart Diseases
Cardiovascular Diseases
Coronary Artery Disease
Heart Failure
Myocardial Ischemia
Aortic Valve Stenosis
Mitral Valve Insufficiency

Heart Disease trials near Toronto, ON, CAN:

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

) application in patients with symptomatic heart disease due to failure of a surgical or transcatheter bioprosthetic aortic valve w...

Invitation-only
Heart Valve Diseases
Aortic Valve Disease
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System
Abbott
Abbott

Toronto, Ontario, Canada and 66 other locations

Familial Hypercholesterolemia (HeFH) or Premature Coronary Artery Disease (CAD) Who Require Additional Lowering of LDL-C. VERVE-102 Uses Bas...

Enrolling
Premature Coronary Heart Disease
Heterozygous Familial Hypercholesterolemia
Drug: VERVE-102

Phase 1

Verve Therapeutics

Toronto, Canada and 14 other locations

Multi-center, prospective, randomized controlled study comparing PCI guided by angiography versus iFR Co-Registration using commercially available Ph...

Invitation-only
Ischemic Heart Disease
Coronary Artery Disease
Device: Philips SyncVision system with Philips pressure wires
Procedure: standard of care angiographically-guided PCI
Philips
Philips

Toronto, Canada and 83 other locations

with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac...

Active, not recruiting
Chronic Kidney Disease
Cardiac Disease
Drug: Placebo
Drug: Ravulizumab

Phase 3

Alexion Pharmaceuticals
Alexion Pharmaceuticals

Toronto, Ontario, Canada and 163 other locations

The purpose of this study is to further evaluate the safety and effectiveness of the Harmony™ TPV system. The Pivotal/CAS phases of the study have tr...

Active, not recruiting
Congenital Heart Disease
Tetrology of Fallot
Device: Harmony TPV System
Medtronic
Medtronic

Toronto, Ontario, Canada and 11 other locations

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Covidien
Covidien

Toronto, Ontario, Canada and 84 other locations

A multi-center, randomized trial to examine the effect of aggressive risk factor control and arrhythmia trigger-based intervention on recurrence of a...

Enrolling
Atrial Fibrillation
Other: Aggressive Risk Factor Control
Other: Standard of Care
Nova Scotia Health Authority (NSHA)

Toronto, Ontario, Canada and 16 other locations

Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect

Active, not recruiting
Heart Defects, Congenital
Cardiovascular Diseases
Device: reSept ASD Occluder
atHeart Medical

Toronto, Canada and 31 other locations

The purpose of this study is to establish the safety and effectiveness of pulsed field ablation as a first-line ablation treatment for subjects with...

Active, not recruiting
Persistent Atrial Fibrillation
Device: FARAPULSE™ Pulsed Field Ablation (PFA) System
Drug: Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Boston Scientific
Boston Scientific

Hamilton, Ontario, Canada and 61 other locations

of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart...

Enrolling
Heart Valve Diseases
Cardiovascular Diseases
Other: Guideline Directed Heart Failure Medication
Device: Carillon Mitral Contour System
Cardiac Dimensions

Toronto, Ontario, Canada and 74 other locations

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