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The purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...
Phase 2
Shelby, North Carolina, United States and 85 other locations
The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...
Phase 2
Gastonia, North Carolina, United States and 62 other locations
tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...
Phase 2, Phase 3
Charlotte, North Carolina, United States and 330 other locations
The goal of this clinical trial is to observe the safety of IGT-303 in healthy volunteers and participants with Chronic Kidney Disease...
Phase 1, Phase 2
Statesville, North Carolina, United States and 12 other locations
to evaluate efficacy, safety and tolerability of treatment with zibotentan/dapagliflozin and dapagliflozin alone in participants with chronic kidney...
Phase 3
Statesville, North Carolina, United States and 297 other locations
This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled multicenter study to investigate outcomes with elecoglipron compare...
Phase 3
Statesville, North Carolina, United States and 711 other locations
and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...
Phase 3
Statesville, North Carolina, United States and 758 other locations
disease (ASCVD) or diabetes with end stage kidney disease (ESKD) undergoing maintenance dialysis....
Phase 2, Phase 3
Charlotte, North Carolina, United States and 564 other locations
The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN.This s...
Phase 3
Statesville, North Carolina, United States and 565 other locations
IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with ...
Houston, North Carolina, United States and 6 other locations
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