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Find clinical trials for Kidney Disease in Durham, NC

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Related conditions:

Kidney Diseases
Chronic Renal Insufficiency
Chronic Kidney Failure
IGA Glomerulonephritis
Renal Insufficiency
Renal Cell Carcinoma
Carcinoma

Kidney Disease trials near Durham, NC, USA:

A Phase 2 Study of MZE829 in Adults with APOL1 Kidney Disease

This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease...

Enrolling
Proteinuric Kidney Disease
Drug: MZE829

Phase 2

Maze Therapeutics

Greensboro, North Carolina, United States and 21 other locations

purpose of the study is to evaluate the efficacy, safety, and tolerability of Inaxaplin (IXP) in participants with proteinuric APOL1- mediated kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Inaxaplin

Phase 2

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Chapel Hill, North Carolina, United States and 26 other locations

The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease...

Enrolling
APOL1-Mediated Kidney Disease
Combination Product: Placebo
Device: APOL1 Genotyping Clinical Trial Assay

Phase 2

AstraZeneca
AstraZeneca

Durham, North Carolina, United States and 71 other locations

tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Phase 2, Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Durham, North Carolina, United States and 325 other locations

in African American/Blacks with APOL1- associated focal segmental glomerulosclerosis (FSGS) and non-diabetic APOL1-associated chronic kidney ...

Enrolling
Chronic Kidney Diseases
Drug: Placebo
Drug: Baricitinib

Phase 2

Duke University
Duke University

Durham, North Carolina, United States

This study is open to adults with chronic kidney disease (CKD) that is at risk of getting worse. People who have taken a specific t ...

Enrolling
Chronic Kidney Disease
Drug: Placebo matching vicadrostat
Drug: Vicadrostat

Phase 2

Boehringer Ingelheim
Boehringer Ingelheim

Durham, North Carolina, United States of America and 146 other locations

of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys...

Enrolling
Chronic Kidney Diseases
Type 2 Diabetes Mellitus
Biological: Renal Autologous Cell Therapy (REACT)
Procedure: Sham Comparator

Phase 3

Prokidney

Chapel Hill, North Carolina, United States and 78 other locations

Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial ...

Active, not recruiting
Non-diabetic Chronic Kidney Disease
Drug: Finerenone (BAY94-8862)
Drug: Placebo

Phase 3

Bayer
Bayer

Chapel Hill, North Carolina, United States and 338 other locations

Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys...

Active, not recruiting
Chronic Kidney Disease
Type 1 Diabetes Mellitus
Other: Placebo
Drug: Finerenone

Phase 3

Bayer
Bayer

Chapel Hill, North Carolina, United States and 80 other locations

and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney...

Enrolling
Chronic Kidney Disease and Hypertension
Drug: Baxdrostat/dapagliflozin
Drug: Placebo/dapagliflozin

Phase 3

AstraZeneca
AstraZeneca

Raleigh, North Carolina, United States and 698 other locations

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