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Find clinical trials for Leukemia in Birmingham, AL

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Related conditions:

Myeloid Leukemia
Acute Myeloid Leukemia
Lymphoid Leukemia
B-Cell Chronic Lymphocytic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lymphoma
Myelodysplastic Syndromes

Leukemia trials near Birmingham, AL, USA:

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients with Relapsed or Refractory Acute Myeloid Leukemia (TUSCANY)

in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic syndromes with increased blasts grade 2...

Enrolling
Leukemia, Myeloid, Acute
Chronic Myelomonocytic Leukemia
Drug: Venetoclax Oral Tablet
Drug: Tuspetinib

Phase 1, Phase 2

Aptose Biosciences

Birmingham, Alabama, United States and 33 other locations

GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (AML). The main aims...

Enrolling
Leukemia
Drug: GDX012
Drug: Chemotherapy Agents

Phase 1, Phase 2

Takeda
Takeda

Birmingham, Alabama, United States and 13 other locations

chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of the study will optimize the dose of study drug (rux...

Active, not recruiting
Leukemia
Drug: Methotrexate
Drug: Thioguanine

Phase 2

Incyte
Incyte

Birmingham, Alabama, United States and 110 other locations

phase I study to determine the maximum tolerated dose of adding Loncastuximab Tesirine to Aclabrutinib in the treatment of chronic lymphocytic leukemia...

Enrolling
Chronic Lymphocytic Leukemia
Drug: Loncastuximab Tesirine and Acalabrutinib

Phase 1

Mayur Narkhede

Birmingham, Alabama, United States

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with Ph+ Chronic Myeloid Leukemia...

Enrolling
Chronic Myeloid Leukemia
Drug: KRT-232
Drug: Dasatinib

Phase 1, Phase 2

Kartos Therapeutics
Kartos Therapeutics

Birmingham, Alabama, United States and 25 other locations

safety, tolerability, pharmacokinetics, pharmacodynamics, and anti-tumor activity of DR-01 in adult patients with large granular lymphocytic leukemia...

Enrolling
LGLL - Large Granular Lymphocytic Leukemia
Aggressive NK Cell Leukemia
Drug: DR-01

Phase 1, Phase 2

Dren Bio

Birmingham, Alabama, United States and 33 other locations

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed therapies (...

Enrolling
Leukemia, Myeloid, Acute
Drug: Cytarabine
Drug: Bleximenib

Phase 1

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Birmingham, Alabama, United States and 32 other locations

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orall...

Active, not recruiting
Blastic Phase Chronic Myelogenous Leukemia
Chronic Phase Chronic Myelogenous Leukemia
Drug: Bosutinib

Phase 1, Phase 2

Children's Oncology Group

Birmingham, Alabama, United States and 44 other locations

This will be a multicenter Phase II open-label study of asciminib in CML-CP patients who have been previously treated with one prior ATP- binding sit...

Active, not recruiting
Chronic Myelogenous Leukemia - Chronic Phase
Drug: asciminib

Phase 2

Novartis
Novartis

Birmingham, Alabama, United States and 79 other locations

In this study, adults with newly-diagnosed Philadelphia Chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) will receive first-line t...

Active, not recruiting
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
Drug: Cytarabine
Drug: Vincristine

Phase 3

Takeda
Takeda

Birmingham, Alabama, United States and 91 other locations

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