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combination) vs durvalumab in limited-stage (LS)-small-cell lung cancer (SCLC) participants.The main goals of this study are to:* E...
Phase 2
Arlington Heights, Illinois, United States and 29 other locations
a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung...
Phase 2
Chicago, Illinois, United States and 84 other locations
The purpose of this study is to assess the objective response rate (ORR) of immunotherapy-based combination therapy and to assess the safety and tole...
Phase 2
Chicago, Illinois, United States and 50 other locations
This is a phase 3, open-label, 4-cohort study (3 randomized cohorts and 1 single-arm cohort). Participants enrolled in each cohort will be treated as...
Phase 3
Tinley Park, Illinois, United States and 30 other locations
The primary objective of this study is to evaluate the safety and tolerability of subcutaneous (SC) tarlatamab.
Phase 1
Chicago, Illinois, United States and 30 other locations
The standard or usual treatment for this disease is pembrolizumab given by needle into the veins (IV).Some cancers shed DNA (circulating tum...
Phase 2, Phase 3
Chicago, Illinois, United States and 9 other locations
HCC is a common cancer worldwide and a leading cause of cancer-related death. Lung cancer is the most frequently ...
Phase 1
Chicago, Illinois, United States and 20 other locations
N2) NSCLC (per the 8th International Association for the Study of Lung Cancer classification). The primary objective of this study ...
Phase 2
Chicago, Illinois, United States and 8 other locations
with previously treated advanced or metastatic non-small cell lung cancer (NSCLC) with or without actionable genomic alterations....
Phase 3
Chicago, Illinois, United States and 210 other locations
Phase 2 Platform Study in Patients with Advanced Non-Small Lung Cancer who progressed on First-Line Osimertinib Therapy. This study...
Phase 2
Chicago, Illinois, United States and 46 other locations
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