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Find clinical trials for Lung Cancer in Durham, NC

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Related conditions:

Non-Small-Cell Lung Carcinoma
Cancer
Small Cell Lung Carcinoma
Carcinoma
Colorectal Cancer
Squamous Cell Carcinoma of Head and Neck
Neoplasm Metastasis

Lung Cancer trials near Durham, NC, USA:

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung...

Enrolling
Metastatic Non Small Cell Lung Cancer
Biological: LN-145

Phase 2

Iovance Biotherapeutics

Chapel Hill, North Carolina, United States and 83 other locations

results observed in participants with Extensive-stage Small Cell Lung Cancer (ES-SCLC) who received at least 1 prior line of platin...

Active, not recruiting
Extensive-stage Small-cell Lung Cancer
Drug: Ifinatamab Deruxtecan (I-DXd)

Phase 2

Daiichi Sankyo
Daiichi Sankyo

Durham, North Carolina, United States of America and 57 other locations

The goal of this Phase 1 clinical study is test tumor infiltrating lymphocytes (known as C-TIL051) with NKTR-255 and anti-PD1 therapy for su ...

Enrolling
Metastatic Non Small Cell Lung Cancer
Biological: C-TIL051

Phase 1

AbelZeta Inc.

Raleigh, North Carolina, United States and 3 other locations

The main aim of this study is to:* evaluate safety and efficacy (per Response Evaluation Criteria in Solid Tumors version 1.1 \[RECIST 1.1\]...

Active, not recruiting
Relapsed/Refractory Small Cell Lung Cancer
Drug: Tarlatamab

Phase 2

Amgen
Amgen

Durham, North Carolina, United States and 80 other locations

This is a phase 1, single-center, open-label study that enrolls adult subjects with extensive stage lung cancer or stage IV non-sma ...

Enrolling
Lung Cancer
Non Small Cell Lung Cancer
Biological: iC9.GD2.CAR.IL-15 T Infusion

Early Phase 1

UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, United States of America

overall response rate (ORR) when compared to nivolumab plus PDCT in participants with previously untreated Stage IV or recurrent non-small cell lung...

Active, not recruiting
Metastatic Non-small Cell Lung Cancer
Non-small Cell Lung Cancer
Drug: Nab-Paclitaxel
Drug: Cisplatin

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Durham, North Carolina, United States and 126 other locations

survival compared with carboplatin, etoposide, and nivolumab alone in newly diagnosed participants with extensive-stage small cell lung cancer...

Active, not recruiting
Extensive-stage Small Cell Lung Cancer
Drug: Etoposide
Drug: Carboplatin

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Durham, North Carolina, United States and 38 other locations

Non-Squamous Non-Small Cell Lung Cancer (NSCLC) remains a leading cause of cancer mortality worldwide, with poor survival ...

Enrolling
Non-Small Cell Lung Cancer
Drug: Carboplatin
Drug: Livmoniplimab

Phase 2, Phase 3

AbbVie
AbbVie

Greensboro, North Carolina, United States and 60 other locations

This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...

Active, not recruiting
Small Cell Lung Cancer
Drug: Durvalumab
Other: Placebo

Phase 3

AstraZeneca
AstraZeneca

Chapel Hill, North Carolina, United States and 182 other locations

KRAS G12C inhibitors (sotorasib or adagrasib) in participants with KRAS G12C-positive (KRAS G12C +) advanced or metastatic non-small cell lung...

Enrolling
KRAS G12C Lung Cancer
Non-Small Cell Lung Cancer
Drug: Sotorasib
Drug: Divarasib

Phase 3

Roche
Roche

Chapel Hill, North Carolina, United States of America and 255 other locations

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