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a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung...
Phase 2
Chapel Hill, North Carolina, United States and 83 other locations
results observed in participants with Extensive-stage Small Cell Lung Cancer (ES-SCLC) who received at least 1 prior line of platin...
Phase 2
Durham, North Carolina, United States of America and 57 other locations
The goal of this Phase 1 clinical study is test tumor infiltrating lymphocytes (known as C-TIL051) with NKTR-255 and anti-PD1 therapy for su ...
Phase 1
Raleigh, North Carolina, United States and 3 other locations
The main aim of this study is to:* evaluate safety and efficacy (per Response Evaluation Criteria in Solid Tumors version 1.1 \[RECIST 1.1\]...
Phase 2
Durham, North Carolina, United States and 80 other locations
This is a phase 1, single-center, open-label study that enrolls adult subjects with extensive stage lung cancer or stage IV non-sma ...
Early Phase 1
Chapel Hill, North Carolina, United States of America
overall response rate (ORR) when compared to nivolumab plus PDCT in participants with previously untreated Stage IV or recurrent non-small cell lung...
Phase 2
Durham, North Carolina, United States and 126 other locations
survival compared with carboplatin, etoposide, and nivolumab alone in newly diagnosed participants with extensive-stage small cell lung cancer...
Phase 2
Durham, North Carolina, United States and 38 other locations
Non-Squamous Non-Small Cell Lung Cancer (NSCLC) remains a leading cause of cancer mortality worldwide, with poor survival ...
Phase 2, Phase 3
Greensboro, North Carolina, United States and 60 other locations
This is a Phase III, Randomized, Double-blind, Placebo-controlled, Multi-center, International Study of Durvalumab or Durvalumab and Tremelimumab as...
Phase 3
Chapel Hill, North Carolina, United States and 182 other locations
KRAS G12C inhibitors (sotorasib or adagrasib) in participants with KRAS G12C-positive (KRAS G12C +) advanced or metastatic non-small cell lung...
Phase 3
Chapel Hill, North Carolina, United States of America and 255 other locations
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