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Therapy with chimeric antigen receptor T (CAR-T) cells has demonstrated activity against refractory lymphoma, however not all tumors respond...
Phase 1
Cleveland, Ohio, United States and 1 other location
chimeric antigen receptor (CAR) targeting cluster of differentiation (CD)19 and CD20 in participants with aggressive large B-cell lymphoma....
Phase 1, Phase 2
Cleveland, Ohio, United States and 25 other locations
patients diagnosed with advanced Relapsed/Refractory non-Hodgkin's lymphoma to determine if ARV-393 may be a possible treatment option.ARV-3...
Phase 1
Cleveland, Ohio, United States and 16 other locations
TrAVeRse is a multicentre, open-label, Phase II study of AVR in treatment naïve MCL participants. The primary objective will be to assess the rate of...
Phase 2
Cleveland, Ohio, United States and 28 other locations
The purpose of this study is to evaluate the safety and pharmacokinetics of eflapegrastim in pediatric participants with solid tumors or lymphoma...
Phase 2
Cleveland, Ohio, United States and 4 other locations
The primary objective of this study is to characterize the safety and tolerability of loncastuximab tesirine in combination with polatuzumab vedotin,...
Phase 1
Cleveland, Ohio, United States and 41 other locations
This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/...
Phase 2
Cleveland, Ohio, United States and 48 other locations
in treating adults with relapsed/refractory (R/R) mantle cell lymphoma (MCL). This study will also look at the safety of sonrotoclax plus za...
Phase 3
Cleveland, Ohio, United States and 149 other locations
2 cohorts to assess safety and efficacy of emavusertib in combination with ibrutinib in participants with R/R primary central nervous system lymphoma...
Phase 1, Phase 2
Cleveland, Ohio, United States and 42 other locations
The purpose of this trial is to measure the following in participants with relapsed and/or refractory B-cell lymphoma who receive epcoritama...
Phase 1, Phase 2
Cleveland, Ohio, United States and 84 other locations
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