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This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma...
Phase 3
L'Hospitalet de Llobregat, Barcelona, Spain and 74 other locations
The goal of this clinical trial is to learn how roginolisib works in comparison to standard treatment in adult patients with uveal/ocular melanoma...
Phase 2
Barcelona, Spain and 15 other locations
There is a lack of strategies for patients who progress after responding to PD-1/l-1 in melanoma. High expression of Nectin4 in skin and melanomas...
Phase 2
Barcelona, Barcelona, Spain and 12 other locations
manner the recurrence-free survival (RFS) of Stage IIIB/C/D melanoma patients with respect to the standard of care (surgery and adjuvant the...
Phase 3
Barcelona, Barcelona, Spain and 36 other locations
binimetinib, and pembrolizumab) given together for the treatment of melanoma that:* is advanced or metastatic (spread to other parts of the ...
Phase 3
Barcelona, Spain and 132 other locations
therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma...
Phase 3
Barcelona, Spain and 71 other locations
medicines (ipilimumab and nivolumab) given for the treatment of melanoma.Melanoma is a type of cancer that starts in the cells that...
Phase 2
Barcelona, Barcelona [barcelona], Spain and 23 other locations
the efficacy and safety of 12 months of encorafenib in combination with binimetinib in adjuvant setting of BRAF V600E/K mutant stage IIB/C melanoma...
Phase 3
Barcelona, Spain and 154 other locations
alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...
Phase 3
Barcelona, Spain and 71 other locations
Brain metastases in patients with advanced and metastatic melanoma are a frequent complication and a significant cause of morbidity and mort...
Phase 2
Barcelona, Barcelona, Spain and 18 other locations
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