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alone in participants with untreated, unresectable or metastatic melanoma. Participants randomized to the pembrolizumab monotherapy arm who ...
Phase 3
Louisville, Kentucky, United States and 71 other locations
This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma...
Phase 1, Phase 2
Louisville, Kentucky, United States and 9 other locations
treatment for patients with unresectable Stage IIIb-IV cutaneous melanoma whose disease progressed on an anti PD-1 and an anti-CTLA-4 contai...
Phase 3
Louisville, Kentucky, United States and 48 other locations
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...
Phase 2
Louisville, Kentucky, United States and 52 other locations
This study is open to adults with advanced cancer (solid tumours) for whom previous treatment was not successful, or no treatment exists. The study t...
Phase 1
Louisville, Kentucky, United States and 4 other locations
This is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors.
Phase 1, Phase 2
Louisville, Kentucky, United States of America and 8 other locations
A prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL \[LN-144/LN-145 (l...
Phase 2
Louisville, Kentucky, United States and 44 other locations
TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase...
Phase 1
Louisville, Kentucky, United States and 39 other locations
QUILT-3.055 is a Phase 2b, open-label, multicohort study investigating combination immunotherapies in patients with advanced solid tumors who have pr...
Phase 2
Louisville, Kentucky, United States and 34 other locations
Phase 1/2 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of SNS-101, a novel anti VISTA IgG1 monoclonal...
Phase 1, Phase 2
Louisville, Kentucky, United States and 9 other locations
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