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Find clinical trials for Multiple Sclerosis (MS) in Orlando, FL

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Related conditions:

Multiple Sclerosis
Sclerosis
Chronic Progressive Multiple Sclerosis
Relapsing-Remitting Multiple Sclerosis
Autoimmune Diseases
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Multiple Sclerosis (MS) trials near Orlando, FL, USA:

Status recently updated

A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

Orelabrutinib is a CNS-penetrable BTK inhibitor. This is a phase 3, randomized, double-blind, parallel-group, multicenter study to evaluate the effic...

Not yet enrolling
Enrolling
Multiple Sclerosis (MS) Primary Progressive
Drug: Orelabrutinib
Drug: Placebo

Phase 3

Zenas BioPharma

Maitland, Florida, United States and 1 other location

SC reference formulation in participants with either relapsing multiple sclerosis (RMS) or primary progressive multiple sc...

Enrolling
Multiple Sclerosis
Drug: Ocrelizumab Reference Formulation
Drug: Ocrelizumab Test Formulation

Phase 2

Roche
Roche

Maitland, Florida, United States and 12 other locations

This study will evaluate if relapsing-remitting MS patients that have not had a relapse in the past year would benefit from a switch to ofat...

Enrolling
Relapsing-Remitting Multiple Sclerosis
Drug: Disease modifying treatment (DMT)
Drug: Ofatumumab

Phase 4

Novartis
Novartis

Orlando, Florida, United States and 42 other locations

The goal of this clinical trial is to learn if drug CYB704, a proposed biosimilar to Ocrevus, works to treat multiple sclerosis in ...

Enrolling
Relapsing Multiple Sclerosis
Biological: Ocrevus-EU
Biological: CYB704

Phase 3

Sandoz
Sandoz

Maitland, Florida, United States and 28 other locations

This study will evaluate the impact of ofatumumab in Relapsing Remitting Multiple Sclerosis (RRMS) participants that are very early...

Active, not recruiting
Relapse Remitting Multiple Sclerosis
Drug: Ofatumumab

Phase 4

Novartis
Novartis

Orlando, Florida, United States and 35 other locations

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...

Enrolling
Relapsing Multiple Sclerosis
Drug: Teriflunomide
Drug: Remibrutinib

Phase 3

Novartis
Novartis

Orlando, Florida, United States and 241 other locations

To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...

Enrolling
Relapsing Multiple Sclerosis
Drug: Remibrutinib
Drug: Teriflunomide

Phase 3

Novartis
Novartis

Orlando, Florida, United States and 249 other locations

of remibrutinib after switching from ocrelizumab and compared to continuous ocrelizumab treatment, in patients living with relapsing multiple...

Enrolling
Relapsing Multiple Sclerosis
Drug: Remibrutinib oral treatment
Drug: Ocrelizumab

Phase 3

Novartis
Novartis

Altamonte Springs, Florida, United States and 27 other locations

This is a Phase 3 extension, global, multicenter study to assess the long-term safety and tolerability of tolebrutinib in adult participants (aged ≥1...

Enrolling
Secondary Progressive Multiple Sclerosis
Relapsing Multiple Sclerosis
Drug: Teriflunomide
Drug: Placebo

Phase 3

Sanofi
Sanofi

Maitland, Florida, United States and 352 other locations

) neo-antigen in subjects with relapsing multiple sclerosis (RMS).COVID-19 sub-study:The purpose of this research sub-study is to e...

Active, not recruiting
Relapsing Multiple Sclerosis
Biological: 23-valent pneumococcal polysaccharide vaccine (23-PPV)
Biological: Tetanus toxoid (TT) containing vaccine (Td, Tdap)

Phase 3

Novartis
Novartis

Maitland, Florida, United States and 299 other locations

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