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Orelabrutinib is a CNS-penetrable BTK inhibitor. This is a phase 3, randomized, double-blind, parallel-group, multicenter study to evaluate the effic...
Phase 3
Maitland, Florida, United States and 1 other location
SC reference formulation in participants with either relapsing multiple sclerosis (RMS) or primary progressive multiple sc...
Phase 2
Maitland, Florida, United States and 55 other locations
This study will evaluate if relapsing-remitting MS patients that have not had a relapse in the past year would benefit from a switch to ofat...
Phase 4
Orlando, Florida, United States and 42 other locations
The goal of this clinical trial is to learn if drug CYB704, a proposed biosimilar to Ocrevus, works to treat multiple sclerosis in ...
Phase 3
Maitland, Florida, United States and 40 other locations
The purpose of this study is to provide efficacy and safety data for remibrutinib in patients with secondary progressive multiple sclerosis...
Phase 3
Orlando, Florida, United States and 163 other locations
To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...
Phase 3
Orlando, Florida, United States and 202 other locations
To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis (RMS)...
Phase 3
Orlando, Florida, United States and 225 other locations
compared with placebo in patients with non-active Secondary Progress MS. Patients will be treated for approximately 24 to 60 months, with a ...
Phase 3
Maitland, Florida, United States and 4 other locations
of frexalimab q4w in male and female participants with RMS and nrSPMS (aged 18 to 60 years at the time of enrollment). People diagnosed with MS...
Phase 3
Altamonte Springs, Florida, United States and 17 other locations
of remibrutinib after switching from ocrelizumab and compared to continuous ocrelizumab treatment, in patients living with relapsing multiple...
Phase 3
Orlando, Florida, United States and 98 other locations
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