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The primary objective of this study is to characterize the safety and tolerability of loncastuximab tesirine in combination with polatuzumab vedotin,...
Phase 1
Pittsburgh, Pennsylvania, United States and 40 other locations
efficacy of combination Golcadomide and nivolumab in patients with non-Hodgkin lymphoma (NHL) who have experienced refract...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States
This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/...
Phase 2
Pittsburgh, Pennsylvania, United States and 58 other locations
receptor (CAR) T-cell therapy, targeting both cluster of differentiation (CD) CD19 and CD20 for the treatment of adult participants with B-Cell non...
Phase 1
Pittsburgh, Pennsylvania, United States and 27 other locations
pharmacokinetic, pharmacodynamic, and clinical activity of AZD0486, a CD19 x CD3 T-cell engaging bispecific antibody, in subjects with B-cell non...
Phase 1
Pittsburgh, Pennsylvania, United States and 28 other locations
This study evaluates a fenretinide phospholipid suspension for the treatment of T-cell non-Hodgkin's lymphoma (NHL)....
Phase 1
Pittsburgh, Pennsylvania, United States and 8 other locations
with polatuzumab vedotin in participants with diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and mantle cell lymphoma...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 28 other locations
This is a Phase I/II, multicenter, open-label, dose-escalation study designed to evaluate the efficacy, safety, tolerability and pharmacokinetics (PK...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 37 other locations
monotherapy in adult participants with relapsed/refractory B-cell non-Hodgkin lymphoma (NHL) who have received at least tw...
Phase 2
Pittsburgh, Pennsylvania, United States and 84 other locations
The purpose of this trial is to measure the following in participants with relapsed and/or refractory B-cell lymphoma who receive epcoritama...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 84 other locations
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