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Find clinical trials for Pancreatic Cancer in London, England

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Pancreatic Cancer trials near London, England, GBR:

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer (ENACT)

is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic...

Enrolling
Locally Advanced Pancreatic Adenocarcinoma
Drug: Modified FOLFIRINOX
Combination Product: Acoustic Cluster Therapy

Phase 2

EXACT Therapeutics

Hammersmith, London, United Kingdom and 9 other locations

Locations recently updated

The goal of this interventional study is to evaluate if the novel diagnostic blood test, called Avantect can early detect pancreatic cancer...

Enrolling
Pancreatic Cancer, Adult
Diabetes Mellitus
Device: Avantect Pancreatic Cancer Test
University Hospital Southampton NHS Foundation Trust

London, United Kingdom and 30 other locations

This is an open-label, multi-centre, randomised, stratified, phase IIb clinical trial of ATRA administered in combination with gemcitabine and nab-pa...

Active, not recruiting
Pancreatic Cancer
Drug: nab-paclitaxel
Drug: Gemcitabine

Phase 2

Queen Mary University of London

London, United Kingdom

phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety pr...

Enrolling
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: AMG 193
Drug: Gemcitabine

Phase 1

Amgen
Amgen

London, United Kingdom and 76 other locations

or without SBP-101 in subjects previously untreated for metastatic pancreatic ductal adenocarcinoma (PDA), including subjects who have recei...

Enrolling
Pancreatic Cancer Metastatic
Pancreatic Cancer Stage IV
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 2, Phase 3

Panbela Therapeutics

London, City Of London, United Kingdom and 91 other locations

is to assess the safety and efficacy of OncoSil™ when given in addition to standard FOLFIRINOX chemotherapy for treatment of Locally Advanced Pancreatic...

Active, not recruiting
Locally Advanced Pancreatic Cancer
Device: OncoSil™
Drug: FOLFIRINOX chemotherapy

Phase 2

OncoSil Medical

London, United Kingdom and 13 other locations

The purpose of the study is to explore the safety and effects of the study drug (PF-08046876) in people diagnosed with advanced cancer of th...

Enrolling
Esophageal Cancer
Pancreatic Adenocarcinoma
Drug: PF-08046876

Phase 1

Pfizer
Pfizer

London, United Kingdom and 27 other locations

This is a study designed to assess the safety, tolerability, pharmacokinetics and preliminary efficacy of WEF-001 as monotherapy in patients with Adv...

Enrolling
Advanced or Metastatic KRAS-mutant Tumor in Non Small Cell Lung Cancer
Advanced Solid Tumors
Drug: WEF-001

Phase 1, Phase 2

Auricula Biosciences Inc.

Headington, Oxford, United Kingdom and 3 other locations

This is a multi-centre, investigator-initiated, dose escalation, Phase I trial of the combination of the FAK inhibitor, Defactinib (VS-6063), and the...

Active, not recruiting
Low Grade Serous Ovarian Cancer
Pancreatic Cancer
Drug: VS-6766
Drug: Defactinib

Phase 1

Institute of Cancer Research, United Kingdom

London, United Kingdom and 4 other locations

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer age....

Active, not recruiting
Breast Cancer
Biliary Cancer
Drug: Camizestrant
Drug: T- Dxd

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Sutton, United Kingdom and 67 other locations

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