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Find clinical trials for Pancreatic Cancer in Nashville, TN

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Stomach Cancer
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Neoplasm Metastasis
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Pancreatic Cancer trials near Nashville, TN, USA:

Locations recently updated

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic...

Enrolling
Pancreatic Ductal Adenocarcinoma (PDAC)
G12D Mutated KRAS
Drug: VS-7375
Drug: cetuximab (or panitumumab if α-gal IgE+ or cetuximab reaction)

Phase 2

Verastem

Nashville, Tennessee, United States and 30 other locations

/ SAR449336, a pan-KRAS inhibitor, in participants with advanced Pancreatic Cancer, Non-Small Cell Lung Cancer, or Colorec...

Enrolling
Pancreatic Ductal Adenocarcinoma
Non-Small Cell Lung Cancer
Drug: BLU-924

Phase 1, Phase 2

Blueprint Medicines

Nashville, Tennessee, United States and 15 other locations

This phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread...

Enrolling
Metastatic Pancreatic Carcinoma
Stage IV Pancreatic Cancer AJCC v8
Drug: Pemigatinib
Procedure: Bone Scan

Phase 2

Sameek Roychowdhury

Nashville, Tennessee, United States and 108 other locations

phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety...

Active, not recruiting
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 1

Amgen
Amgen

Nashville, Tennessee, United States and 76 other locations

1) patients with newly diagnosed, advanced, unresectable colorectal cancer (CRC) or 2) patients with newly diagnosed, advanced, unresectable ...

Enrolling
Cancer Weight Loss
Drug: TCMCB07
Drug: Placebo

Phase 2

Endevica Bio

Nashville, Tennessee, United States and 25 other locations

or without SBP-101 in subjects previously untreated for metastatic pancreatic ductal adenocarcinoma (PDA), including subjects who have recei...

Enrolling
Pancreatic Cancer Metastatic
Pancreatic Cancer Stage IV
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 2, Phase 3

Panbela Therapeutics

Nashville, Tennessee, United States and 91 other locations

This is a nonrandomized, uncontrolled, open-label, multicenter Phase 2 study to evaluate the efficacy, safety, and tolerability of futibatinib in com...

Active, not recruiting
Siewert Type 1 GEJ Cancer
Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal Cancer
Drug: Oxaliplatin
Drug: Futibatinib

Phase 2

Taiho Pharma
Taiho Pharma

Nashville, Tennessee, United States and 21 other locations

The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combinatio...

Enrolling
Pancreatic Cancer Metastatic
Pancreatic Adenocarcinoma Metastatic
Drug: daraxonrasib
Drug: nab-paclitaxel

Phase 3

Revolution Medicines
Revolution Medicines

Nashville, Tennessee, United States of America and 81 other locations

Locations recently updated

The purpose of this study is to evaluate the safety and efficacy of atebimetinib in combination with modified GnP compared with SOC GnP alone.

Enrolling
Pancreatic Cancer Metastatic
Pancreatic Adenocarcinoma Metastatic
Drug: mGnP
Drug: GnP

Phase 3

Immuneering Corporation

Nashville, Tennessee, United States and 58 other locations

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.

Enrolling
Resected Pancreatic Adenocarcinoma
PDAC - Pancreatic Ductal Adenocarcinoma
Drug: daraxonrasib

Phase 3

Revolution Medicines
Revolution Medicines

Nashville, Tennessee, United States of America and 77 other locations

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