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Find clinical trials for Prostate Cancer in Philadelphia, PA

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Prostatic Cancer
Breast Cancer
Cancer
Ovarian Cancer
Neoplasm Metastasis
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Colorectal Cancer

Prostate Cancer trials near Philadelphia, PA, USA:

Study of AZD0754 in Participants With Metastatic Prostate Cancer (APOLLO)

of this study is to evaluate the safety, tolerability, and antitumour activity of AZD0754 CAR T-cell therapy in participants with metastatic prostate...

Enrolling
Metastatic Prostate Cancer
Biological: AZD2287
Biological: AZD0754

Phase 1, Phase 2

AstraZeneca
AstraZeneca

Philadelphia, Pennsylvania, United States and 14 other locations

Locations recently updated

and in combination with abiraterone in participants with metastatic prostate cancer. The study includes dose-escalation and cohort ...

Active, not recruiting
Prostate Cancer Metastatic
Drug: Corticosteroid (e.g., prednisone/prednisolone)
Drug: Abiraterone

Phase 1, Phase 2

Novartis
Novartis

Philadelphia, Pennsylvania, United States of America and 16 other locations

pharmacokinetic (PK), pharmacodynamic (PD), and the preliminary efficacy of JANX007 in adults with metastatic castration-resistant prostate ...

Enrolling
Castration Resistant Prostatic Cancer
Metastatic Castration-resistant Prostate Cancer
Biological: JANX007
Drug: Darolutamide

Phase 1

Janux Therapeutics

Philadelphia, Pennsylvania, United States and 35 other locations

Medicines that reduce the amount of testosterone in the body are commonly used to treat prostate cancer. PRL-02 depot is a potentia ...

Enrolling
Metastatic Castration Resistant Prostate Cancer
Metastatic Castration-sensitive Prostate Cancer
Drug: prednisone
Drug: PRL-02 injection

Phase 1

Astellas
Astellas

Bala-Cynwyd, Pennsylvania, United States and 25 other locations

The primary objectives of this study are to evaluate the safety and tolerability of xaluritamig administered as monotherapy or in combination with an...

Enrolling
Prostate Cancer
Drug: GnRH Antagonist
Drug: Xaluritamig

Phase 1

Amgen
Amgen

Philadelphia, Pennsylvania, United States and 8 other locations

this trial is to determine the safety profile of xaluritamig at the proposed regimen in adult participants with metastatic castration-resistant prostate...

Enrolling
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Drug: Xaluritamig

Phase 1

Amgen
Amgen

Philadelphia, Pennsylvania, United States and 10 other locations

Cu 64 PSMA I\&T injection for PET/CT imaging in patients with newly diagnosed unfavorable intermediate high-risk, high-risk or very high-risk prostate...

Active, not recruiting
Prostate Adenocarcinoma
Prostate Cancer
Drug: Copper Cu 64 PSMA I&T

Phase 3

Curium

Princeton, New Jersey, United States and 42 other locations

This study seeks to determine the clinical impact of Gene Expression Classifier (GEC) testing in prostate cancer care while also de...

Active, not recruiting
Prostate Cancer
Device: Oncotype Dx Genomic Prostate Score (GPS)
Device: Prolaris
University of Michigan Rogel Cancer Center
University of Michigan Rogel Cancer Center

Philadelphia, Pennsylvania, United States and 7 other locations

inhibitor, in Veterans with metastatic castration-resistant prostate cancer (mCRPC) characterized by either mismatch repair deficie...

Active, not recruiting
Metastatic Castration Resistant Prostate Cancer
Drug: Pembrolizumab

Phase 2

VA Office of Research and Development
VA Office of Research and Development

Philadelphia, Pennsylvania, United States and 12 other locations

The overall aim of the trial is to evaluate the safety, tolerability, and pharmacokinetics (PK) of AMG 509 (monotherapy and in combination with abira...

Enrolling
Prostate Cancer
Drug: AMG 509
Drug: Abiraterone

Phase 1

Amgen
Amgen

Philadelphia, Pennsylvania, United States and 57 other locations

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