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This study will look to establish the recommended biologic dose of AE37 in combination with pembrolizumab that will enhance the tumor-specif-...
Phase 2
Cleveland, Ohio, United States and 5 other locations
This is a Phase 2, Multi-Cohort, Open-Label, Multi-Center Study. Cohort 1 will be a single-arm study of intratumoral tavokinogene telseplasmid (TAVO)...
Phase 2
Cleveland, Ohio, United States and 13 other locations
with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...
Phase 3
Cleveland, Ohio, United States and 275 other locations
pharmacokinetics, pharmacodynamics, maximum tolerated dose, and anti-tumor effects of AVZO-021 in patients with advanced solid tumors...
Phase 1, Phase 2
Cleveland, Ohio, United States and 9 other locations
This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without du...
Phase 3
Cleveland, Ohio, United States and 297 other locations
to treatment of physician's choice (TPC) in participants with triple-negative breast cancer (TNBC) who received n...
Phase 3
Massillon, Ohio, United States and 226 other locations
(HCC), pancreatic ductal adenocarcinoma (PDAC), biliary tract cancers (BTC), esophageal squamous cell carcinoma (ESCC), triple negative...
Phase 1
Cleveland, Ohio, United States and 53 other locations
This study will test the safety of a drug called PF-08046054/SGN-PDL1V alone and with pembrolizumab in participants with solid tumors. It wi ...
Phase 1
Cleveland, Ohio, United States and 43 other locations
The goal of this clinical trial is to learn if the drug TUB-030 works to treat solid cancer in adults. The study will also explore the safet...
Phase 1, Phase 2
Cleveland, Ohio, United States and 7 other locations
tumors....
Phase 1
Cleveland, Ohio, United States and 10 other locations
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