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Find clinical trials for Triple Negative Breast Cancer in St Louis, MO

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Related conditions:

Breast Cancer
Non-Small-Cell Lung Carcinoma
Squamous Cell Carcinoma of Head and Neck
Cancer
Endometrial Cancer
Ovarian Cancer
Neoplasm Metastasis

Triple Negative Breast Cancer trials near St Louis, MO, USA:

Establishing the Recommended Biological Dose for AE37 Peptide Vaccine in Combination With Pembrolizumab That Will Enhance the Tumor-specific Immune Response and Demonstrate Efficacy in Patients With Advanced Triple-negative Breast Cancer (NSABP FB-14)

This study will look to establish the recommended biologic dose of AE37 in combination with pembrolizumab that will enhance the tumor-specif-...

Active, not recruiting
Triple-negative Breast Cancer
Biological: Pembrolizumab
Biological: AE37 Peptide vaccine

Phase 2

NuGenerex Immuno-Oncology

Swansea, Illinois, United States and 5 other locations

of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple...

Active, not recruiting
Triple Negative Breast Neoplasms
Drug: Capivasertib
Drug: Trastuzumab deruxtecan

Phase 1, Phase 2

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 31 other locations

and nivolumab with neoadjuvant chemotherapy will decrease tumor associated macrophages (TAMs) and increase tumor infiltrating lymph-...

Active, not recruiting
Triple Negative Breast Cancer
Procedure: Tumor biopsy
Biological: Cabiralizumab

Phase 1, Phase 2

The Washington University
The Washington University

Saint Louis, Missouri, United States

(SG) given at an alternative dose and schedule, in participants with triple-negative breast cancer (TNBC).The pri...

Enrolling
Triple Negative Breast Cancer
Drug: Sacituzumab Govitecan-hziy (SG)

Phase 1, Phase 2

Gilead Sciences
Gilead Sciences

St Louis, Missouri, United States and 14 other locations

doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC). Usually, after neoadjuvant therapy and surgery for triple ne ...

Active, not recruiting
Triple Negative Breast Cancer
Drug: Atezolizumab
Drug: Placebo

Phase 3

National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP)

Swansea, Illinois, United States and 216 other locations

Locations recently updated

and capecitabine) for the treatment of first-line metastatic triple-negative breast cancer (TNBC) or estrogen rec...

Enrolling
Breast Neoplasms
Drug: Paclitaxel
Drug: Iza-bren

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

O'Fallon, Illinois, United States and 283 other locations

or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...

Enrolling
Triple Negative Breast Cancer
Drug: Capecitabine
Drug: Sacituzumab govitecan-hziy (SG)

Phase 3

Gilead Sciences
Gilead Sciences

St Louis, Missouri, United States and 283 other locations

(ABBV-181) and/or chemotherapy in participants with selected solid tumors. This study consists of 2 main parts, a dose-escalation phase and ...

Active, not recruiting
Advanced Solid Tumors
Non-small-cell-lung-cancer (NSCLC)
Drug: ABBV-368
Drug: ABBV-927

Phase 1

AbbVie
AbbVie

Saint Louis, Missouri, United States and 26 other locations

with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvan...

Active, not recruiting
Breast Cancer
Drug: Pembrolizumab
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

St Louis, Missouri, United States and 275 other locations

This study is to evaluate the safety and tolerability of JAB-2485 monotherapy in adult participants with advanced solid tumors....

Enrolling
Triple Negative Breast Cancer, TNBC
Small Cell Lung Cancer, SCLC
Drug: JAB-2485 (Aurora A inhibitor)

Phase 1, Phase 2

Jacobio Pharmaceuticals

St Louis, Missouri, United States and 7 other locations

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